Wolan DW - Search Results

1

Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.

Wolan DW, Greasley SE, Wall MJ, Benkovic SJ, Wilson IA. Wolan DW, et al. Biochemistry. 2003 Sep 23;42(37):10904-14. doi: 10.1021/bi030106h. Biochemistry. 2003. PMID: 12974624

2

Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A.

Wolan DW, Teyton L, Rudolph MG, Villmow B, Bauer S, Busch DH, Wilson IA. Wolan DW, et al. Nat Immunol. 2001 Mar;2(3):248-54. doi: 10.1038/85311. Nat Immunol. 2001. PMID: 11224525

3

Structural insights into the avian AICAR transformylase mechanism.

Wolan DW, Greasley SE, Beardsley GP, Wilson IA. Wolan DW, et al. Biochemistry. 2002 Dec 31;41(52):15505-13. doi: 10.1021/bi020505x. Biochemistry. 2002. PMID: 12501179

4

Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor.

Wolan DW, Cheong CG, Greasley SE, Wilson IA. Wolan DW, et al. Biochemistry. 2004 Feb 10;43(5):1171-83. doi: 10.1021/bi030162i. Biochemistry. 2004. PMID: 14756553

5

Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates.

Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Cheong CG, et al. Among authors: wolan dw. J Biol Chem. 2004 Apr 23;279(17):18034-45. doi: 10.1074/jbc.M313691200. Epub 2004 Feb 13. J Biol Chem. 2004. PMID: 14966129 Free article.

6

Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.

Li C, Xu L, Wolan DW, Wilson IA, Olson AJ. Li C, et al. Among authors: wolan dw. J Med Chem. 2004 Dec 30;47(27):6681-90. doi: 10.1021/jm049504o. J Med Chem. 2004. PMID: 15615517

7

Identification and Co-complex Structure of a New S. pyogenes SpeB Small Molecule Inhibitor.

Wang AY, González-Páez GE, Wolan DW. Wang AY, et al. Among authors: wolan dw. Biochemistry. 2015 Jul 21;54(28):4365-73. doi: 10.1021/acs.biochem.5b00607. Epub 2015 Jul 13. Biochemistry. 2015. PMID: 26132413

8

Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin.

Wright ZVF, Wu NC, Kadam RU, Wilson IA, Wolan DW. Wright ZVF, et al. Among authors: wolan dw. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3744-3748. doi: 10.1016/j.bmcl.2017.06.074. Epub 2017 Jun 28. Bioorg Med Chem Lett. 2017. PMID: 28689973 Free PMC article.

9

X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors.

Roncase EJ, González-Páez GE, Wolan DW. Roncase EJ, et al. Among authors: wolan dw. Biochemistry. 2019 Apr 2;58(13):1728-1737. doi: 10.1021/acs.biochem.9b00098. Epub 2019 Mar 14. Biochemistry. 2019. PMID: 30835452

10

An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.

Yao Y, Kadam RU, Lee CD, Woehl JL, Wu NC, Zhu X, Kitamura S, Wilson IA, Wolan DW. Yao Y, et al. Among authors: wolan dw. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18431-18438. doi: 10.1073/pnas.2006893117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690700 Free PMC article.

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