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Identification of novel isoform-selective inhibitors within class I histone deacetylases.
Hu E, Dul E, Sung CM, Chen Z, Kirkpatrick R, Zhang GF, Johanson K, Liu R, Lago A, Hofmann G, Macarron R, de los Frailes M, Perez P, Krawiec J, Winkler J, Jaye M. Hu E, et al. Among authors: perez p. J Pharmacol Exp Ther. 2003 Nov;307(2):720-8. doi: 10.1124/jpet.103.055541. Epub 2003 Sep 15. J Pharmacol Exp Ther. 2003. PMID: 12975486
The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2.
D'Alessandro PL, Corti C, Roth A, Ugolini A, Sava A, Montanari D, Bianchi F, Garland SL, Powney B, Koppe EL, Rocheville M, Osborne G, Perez P, de la Fuente J, De Los Frailes M, Smith PW, Branch C, Nash D, Watson SP. D'Alessandro PL, et al. Among authors: perez p. Bioorg Med Chem Lett. 2010 Jan 15;20(2):759-62. doi: 10.1016/j.bmcl.2009.11.032. Epub 2009 Nov 26. Bioorg Med Chem Lett. 2010. PMID: 20005096
Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure.
Jaye MC, Krawiec JA, Campobasso N, Smallwood A, Qiu C, Lu Q, Kerrigan JJ, De Los Frailes Alvaro M, Laffitte B, Liu WS, Marino JP Jr, Meyer CR, Nichols JA, Parks DJ, Perez P, Sarov-Blat L, Seepersaud SD, Steplewski KM, Thompson SK, Wang P, Watson MA, Webb CL, Haigh D, Caravella JA, Macphee CH, Willson TM, Collins JL. Jaye MC, et al. Among authors: perez p. J Med Chem. 2005 Aug 25;48(17):5419-22. doi: 10.1021/jm050532w. J Med Chem. 2005. PMID: 16107141
Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases.
Payne DJ, Hueso-Rodríguez JA, Boyd H, Concha NO, Janson CA, Gilpin M, Bateson JH, Cheever C, Niconovich NL, Pearson S, Rittenhouse S, Tew D, Díez E, Pérez P, De La Fuente J, Rees M, Rivera-Sagredo A. Payne DJ, et al. Among authors: perez p. Antimicrob Agents Chemother. 2002 Jun;46(6):1880-6. doi: 10.1128/AAC.46.6.1880-1886.2002. Antimicrob Agents Chemother. 2002. PMID: 12019104 Free PMC article.
Bifidobacteria antagonize the life cycle of Clostridioides difficile.
Soldavini Pelichotti PC, Martinefski MR, Boscolo O, Tripodi VP, Lucangioli SE, Trejo FM, Pérez PF. Soldavini Pelichotti PC, et al. Among authors: perez pf. Microb Pathog. 2024 Dec 21;199:107250. doi: 10.1016/j.micpath.2024.107250. Online ahead of print. Microb Pathog. 2024. PMID: 39716653
Adult height in girls with idiopathic central precocious puberty treated with triptorelin.
Corripio R, Soriano-Guillén L, Herrero FJ, Castro-Feijoó L, Escribano A, Sol-Ventura P, Espino R, Vela A, Labarta JI; Spanish PUBERE Group; Argente J. Corripio R, et al. Front Endocrinol (Lausanne). 2024 Dec 5;15:1498726. doi: 10.3389/fendo.2024.1498726. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 39703867 Free PMC article.
The Immunoregulatory Architecture of the Adult Oral Cavity.
Fernandes Matuck B, Huynh K, Pereira D, Zhang X, Kunz M, Kumar N, Easter QT, Fernandes A, Ghodke A, Predeus A, Szabo L, Harnischfeger N, Khavandgar Z, Beach M, Perez P, Nilges B, Moreno M, Ko K, Teichmann S, Kimple A, Pringle S, Kretzschmar K, Warner BM, Sequeira I, Liu J, Byrd KM. Fernandes Matuck B, et al. Among authors: perez p. bioRxiv [Preprint]. 2024 Dec 2:2024.12.01.626279. doi: 10.1101/2024.12.01.626279. bioRxiv. 2024. PMID: 39677739 Free PMC article. Preprint.
1,531 results