Macchia B - Search Results

1

Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alpha- and beta-adrenergic receptors.

Macchia B, Balsamo A, Breschi MC, Lapucci A, Lucacchini A, Macchia F, Manera C, Martinelli A, Martini C, Martinotti E, et al. Macchia B, et al. Among authors: macchia f. J Med Chem. 1992 Mar 20;35(6):1009-18. doi: 10.1021/jm00084a006. J Med Chem. 1992. PMID: 1313109

2

Conformational effects on the activity of drugs. 7. Synthesis and pharmacological properties of 2-(p-nitrophenyl)-substituted morpholines.

Balsamo A, Crotti P, Lapucci A, Macchia B, Macchia F, Del Tacca M, Mazzanti L, Ceserani R. Balsamo A, et al. Among authors: macchia b, macchia f. J Med Chem. 1979 Jun;22(6):738-41. doi: 10.1021/jm00192a023. J Med Chem. 1979. PMID: 37340

3

Molecular orbital studies on the mechanism of drug-receptor interaction. 2. beta-Adrenergic drugs. An approach to explain the role of the aromatic moiety.

Petrongolo C, Macchia B, Macchia F, Martinelli A. Petrongolo C, et al. Among authors: macchia b, macchia f. J Med Chem. 1977 Dec;20(12):1645-53. doi: 10.1021/jm00222a021. J Med Chem. 1977. PMID: 201757

4

Molecular design, synthesis, and antiinflammatory activity of a series of beta-aminoxypropionic acids.

Macchia B, Balsamo A, Lapucci A, Macchia F, Martinelli A, Nencetti S, Orlandini E, Baldacci M, Mengozzi G, Soldani G, et al. Macchia B, et al. Among authors: macchia f. J Med Chem. 1990 May;33(5):1423-30. doi: 10.1021/jm00167a023. J Med Chem. 1990. PMID: 2329564

5

Synthesis and evaluation of the pharmacological activity of rigid analogues of sympathomimetic catecholamines derived from bicyclo[2.2.1]heptane.

Balsamo A, Breschi MC, Lapucci A, Macchia B, Macchia F, Martinotti E, Nencetti S, Nieri P, Orlandini E. Balsamo A, et al. Among authors: macchia b, macchia f. J Med Chem. 1989 Apr;32(4):856-9. doi: 10.1021/jm00124a020. J Med Chem. 1989. PMID: 2539479

6

Synthesis and antimicrobial properties of substituted beta-aminoxypropionyl penicillins and cephalosporins.

Balsamo A, Broccali G, Lapucci A, Macchia B, Macchia F, Orlandini E, Rossello A. Balsamo A, et al. Among authors: macchia b, macchia f. J Med Chem. 1989 Jun;32(6):1398-401. doi: 10.1021/jm00126a041. J Med Chem. 1989. PMID: 2724308

7

An interdisciplinary approach to the design of new structures active at the beta-adrenergic receptor. Aliphatic oxime ether derivatives.

Macchia B, Balsamo A, Lapucci A, Martinelli A, Macchia F, Breschi MC, Fantoni B, Martinotti E. Macchia B, et al. Among authors: macchia f. J Med Chem. 1985 Feb;28(2):153-60. doi: 10.1021/jm00380a001. J Med Chem. 1985. PMID: 2857200

8

Role of the (acyloxy)methyl moiety in eliciting the adrenergic beta-blocking activity of 3-(acyloxy)propanolamines.

Macchia B, Balsamo A, Lapucci A, Macchia F, Martinelli A, Ammon HL, Prasad SM, Breschi MC, Ducci M, Martinotti E. Macchia B, et al. Among authors: macchia f. J Med Chem. 1987 Apr;30(4):616-22. doi: 10.1021/jm00387a006. J Med Chem. 1987. PMID: 2882026

9

An anomalous effect of N-isopropyl substitution in determining beta-adrenergic activity.

Macchia B, Balsamo A, Lapucci A, Macchia F, Manera C, Nencetti S, Breschi MC, Lucacchini A, Martini C, Martinotti E. Macchia B, et al. Among authors: macchia f. Drug Des Deliv. 1988 May;2(4):257-62. Drug Des Deliv. 1988. PMID: 2908223

10

Molecular orbital studies on the mechanism of drug-receptor interaction. 5. Molecular reactivity and receptor affinity of beta-agonist adrenergic drugs.

Macchia B, Martinelli A. Macchia B, et al. Drug Des Deliv. 1988 May;2(4):273-86. Drug Des Deliv. 1988. PMID: 2908224

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