Parnell GD - Search Results

1

Molecular and biological properties of an abrin A chain immunotoxin designed for therapy of human small cell lung cancer.

Wawrzynczak EJ, Zangemeister-Wittke U, Waibel R, Henry RV, Parnell GD, Cumber AJ, Jones M, Stahel RA. Wawrzynczak EJ, et al. Among authors: parnell gd. Br J Cancer. 1992 Aug;66(2):361-6. doi: 10.1038/bjc.1992.271. Br J Cancer. 1992. PMID: 1323991 Free PMC article.

2

Structural features of the antibody-A chain linkage that influence the activity and stability of ricin A chain immunotoxins.

Cumber AJ, Westwood JH, Henry RV, Parnell GD, Coles BF, Wawrzynczak EJ. Cumber AJ, et al. Among authors: parnell gd. Bioconjug Chem. 1992 Sep-Oct;3(5):397-401. doi: 10.1021/bc00017a007. Bioconjug Chem. 1992. PMID: 1329989

3

Cytotoxic activity of ricin A chain immunotoxins recognising cluster 1, w4 and 5A antigens associated with human small cell lung cancer.

Wawrzynczak EJ, Derbyshire EJ, Henry RV, Parnell GD, Smith A, Waibel R, Stahel RA. Wawrzynczak EJ, et al. Among authors: parnell gd. Br J Cancer Suppl. 1991 Jun;14:71-3. Br J Cancer Suppl. 1991. PMID: 1645577 Free PMC article.

4

The effect of ricin B chain on the intracellular trafficking of an A chain immunotoxin.

Timar J, McIntosh DP, Henry R, Cumber AJ, Parnell GD, Davies AJ. Timar J, et al. Among authors: parnell gd. Br J Cancer. 1991 Oct;64(4):655-62. doi: 10.1038/bjc.1991.377. Br J Cancer. 1991. PMID: 1911213 Free PMC article.

5

Comparative biochemical, cytotoxic and pharmacokinetic properties of immunotoxins made with native ricin A chain, ricin A1 chain and recombinant ricin A chain.

Wawrzynczak EJ, Cumber AJ, Henry RV, Parnell GD. Wawrzynczak EJ, et al. Among authors: parnell gd. Int J Cancer. 1991 Jan 2;47(1):130-5. doi: 10.1002/ijc.2910470123. Int J Cancer. 1991. PMID: 1985869

6

Blocked and non-blocked ricin immunotoxins against the CD4 antigen exhibit higher cytotoxic potency than a ricin A chain immunotoxin potentiated with ricin B chain or with a ricin B chain immunotoxin.

Wawrzynczak EJ, Watson GJ, Cumber AJ, Henry RV, Parnell GD, Rieber EP, Thorpe PE. Wawrzynczak EJ, et al. Among authors: parnell gd. Cancer Immunol Immunother. 1991;32(5):289-95. doi: 10.1007/BF01789046. Cancer Immunol Immunother. 1991. PMID: 1998970 Free PMC article.

7

Biochemical, cytotoxic and pharmacokinetic properties of an immunotoxin composed of a mouse monoclonal antibody Fib75 and the ribosome-inactivating protein alpha-sarcin from Aspergillus giganteus.

Wawrzynczak EJ, Henry RV, Cumber AJ, Parnell GD, Derbyshire EJ, Ulbrich N. Wawrzynczak EJ, et al. Among authors: parnell gd. Eur J Biochem. 1991 Feb 26;196(1):203-9. doi: 10.1111/j.1432-1033.1991.tb15805.x. Eur J Biochem. 1991. PMID: 2001699 Free article.

8

Selective cytotoxic effects of a ricin A chain immunotoxin made with the monoclonal antibody SWA11 recognising a human small cell lung cancer antigen.

Wawrzynczak EJ, Derbyshire EJ, Henry RV, Parnell GD, Smith A, Waibel R, Stahel RA. Wawrzynczak EJ, et al. Among authors: parnell gd. Br J Cancer. 1990 Sep;62(3):410-4. doi: 10.1038/bjc.1990.308. Br J Cancer. 1990. PMID: 2169852 Free PMC article.

9

Pharmacokinetics in the rat of a panel of immunotoxins made with abrin A chain, ricin A chain, gelonin, and momordin.

Wawrzynczak EJ, Cumber AJ, Henry RV, May J, Newell DR, Parnell GD, Worrell NR, Forrester JA. Wawrzynczak EJ, et al. Among authors: parnell gd. Cancer Res. 1990 Dec 1;50(23):7519-26. Cancer Res. 1990. PMID: 2253201

10

Purification of immunotoxins containing the ribosome-inactivating proteins gelonin and momordin using high performance liquid immunoaffinity chromatography compared with blue sepharose CL-6B affinity chromatography.

Cumber AJ, Henry RV, Parnell GD, Wawrzynczak EJ. Cumber AJ, et al. Among authors: parnell gd. J Immunol Methods. 1990 Dec 31;135(1-2):15-24. doi: 10.1016/0022-1759(90)90251-p. J Immunol Methods. 1990. PMID: 2273254

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