(Rp)- and (Sp)-8-piperidino-adenosine 3',5'-(cyclic)thiophosphates discriminate completely between site A and B of the regulatory subunits of cAMP-dependent protein kinase type I and II.
Ogreid D, Dostmann W, Genieser HG, Niemann P, Døskeland SO, Jastorff B.
Ogreid D, et al.
Eur J Biochem. 1994 May 1;221(3):1089-94. doi: 10.1111/j.1432-1033.1994.tb18828.x.
Eur J Biochem. 1994.
PMID: 8181466
Free article.
8-Piperidino-cAMP has been shown to bind with high affinity to site A of the regulatory subunit of cAMP-dependent protein kinase type I (AI) whereas it is partially excluded from the homologous site (AII) of isozyme II [Ogreid, D., Ekanger, R., Suva, R. H., Miller, …
8-Piperidino-cAMP has been shown to bind with high affinity to site A of the regulatory subunit of cAMP-dependent protein kinase type I (AI) …