Brady WA - Search Results

1

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4.

Chen L, Ashe S, Brady WA, Hellström I, Hellström KE, Ledbetter JA, McGowan P, Linsley PS. Chen L, et al. Among authors: brady wa. Cell. 1992 Dec 24;71(7):1093-102. doi: 10.1016/s0092-8674(05)80059-5. Cell. 1992. PMID: 1335364

2

CTLA-4 is a second receptor for the B cell activation antigen B7.

Linsley PS, Brady W, Urnes M, Grosmaire LS, Damle NK, Ledbetter JA. Linsley PS, et al. J Exp Med. 1991 Sep 1;174(3):561-9. doi: 10.1084/jem.174.3.561. J Exp Med. 1991. PMID: 1714933 Free PMC article.

3

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

Linsley PS, Brady W, Grosmaire L, Aruffo A, Damle NK, Ledbetter JA. Linsley PS, et al. J Exp Med. 1991 Mar 1;173(3):721-30. doi: 10.1084/jem.173.3.721. J Exp Med. 1991. PMID: 1847722 Free PMC article.

4

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors.

Linsley PS, Greene JL, Brady W, Bajorath J, Ledbetter JA, Peach R. Linsley PS, et al. Immunity. 1994 Dec;1(9):793-801. doi: 10.1016/s1074-7613(94)80021-9. Immunity. 1994. PMID: 7534620

5

Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4). A disulfide-linked homodimer binds two CD86 molecules.

Linsley PS, Nadler SG, Bajorath J, Peach R, Leung HT, Rogers J, Bradshaw J, Stebbins M, Leytze G, Brady W, et al. Linsley PS, et al. J Biol Chem. 1995 Jun 23;270(25):15417-24. doi: 10.1074/jbc.270.25.15417. J Biol Chem. 1995. PMID: 7541042 Free article.

6

Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

Peach RJ, Bajorath J, Brady W, Leytze G, Greene J, Naemura J, Linsley PS. Peach RJ, et al. J Exp Med. 1994 Dec 1;180(6):2049-58. doi: 10.1084/jem.180.6.2049. J Exp Med. 1994. PMID: 7964482 Free PMC article.

7

Single-chain mono- and bispecific antibody derivatives with novel biological properties and antitumour activity from a COS cell transient expression system.

Hayden MS, Linsley PS, Gayle MA, Bajorath J, Brady WA, Norris NA, Fell HP, Ledbetter JA, Gilliland LK. Hayden MS, et al. Among authors: brady wa. Ther Immunol. 1994 Jan;1(1):3-15. Ther Immunol. 1994. PMID: 7584477

8

Expression and function of B7 on human epidermal Langerhans cells.

Symington FW, Brady W, Linsley PS. Symington FW, et al. J Immunol. 1993 Feb 15;150(4):1286-95. J Immunol. 1993. PMID: 7679425

9

Medullary thymic epithelium expresses a ligand for CTLA4 in situ and in vitro.

Nelson AJ, Hosier S, Brady W, Linsley PS, Farr AG. Nelson AJ, et al. J Immunol. 1993 Sep 1;151(5):2453-61. J Immunol. 1993. PMID: 8395547

10

Characterization of human inducible costimulator ligand expression and function.

Aicher A, Hayden-Ledbetter M, Brady WA, Pezzutto A, Richter G, Magaletti D, Buckwalter S, Ledbetter JA, Clark EA. Aicher A, et al. Among authors: brady wa. J Immunol. 2000 May 1;164(9):4689-96. doi: 10.4049/jimmunol.164.9.4689. J Immunol. 2000. PMID: 10779774

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