Akita RW - Search Results

1

Identification of heregulin, a specific activator of p185erbB2.

Holmes WE, Sliwkowski MX, Akita RW, Henzel WJ, Lee J, Park JW, Yansura D, Abadi N, Raab H, Lewis GD, et al. Holmes WE, et al. Among authors: akita rw. Science. 1992 May 22;256(5060):1205-10. doi: 10.1126/science.256.5060.1205. Science. 1992. PMID: 1350381

2

Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin.

Sliwkowski MX, Schaefer G, Akita RW, Lofgren JA, Fitzpatrick VD, Nuijens A, Fendly BM, Cerione RA, Vandlen RL, Carraway KL 3rd. Sliwkowski MX, et al. Among authors: akita rw. J Biol Chem. 1994 May 20;269(20):14661-5. J Biol Chem. 1994. PMID: 7514177 Free article.

3

Her-2/neu expression in node-negative breast cancer: direct tissue quantitation by computerized image analysis and association of overexpression with increased risk of recurrent disease.

Press MF, Pike MC, Chazin VR, Hung G, Udove JA, Markowicz M, Danyluk J, Godolphin W, Sliwkowski M, Akita R, et al. Press MF, et al. Cancer Res. 1993 Oct 15;53(20):4960-70. Cancer Res. 1993. PMID: 8104689

4

The erbB3 gene product is a receptor for heregulin.

Carraway KL 3rd, Sliwkowski MX, Akita R, Platko JV, Guy PM, Nuijens A, Diamonti AJ, Vandlen RL, Cantley LC, Cerione RA. Carraway KL 3rd, et al. J Biol Chem. 1994 May 13;269(19):14303-6. J Biol Chem. 1994. PMID: 8188716 Free article.

5

Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4.

Zhang D, Sliwkowski MX, Mark M, Frantz G, Akita R, Sun Y, Hillan K, Crowley C, Brush J, Godowski PJ. Zhang D, et al. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9562-7. doi: 10.1073/pnas.94.18.9562. Proc Natl Acad Sci U S A. 1997. PMID: 9275162 Free PMC article.

6

Selection of heregulin variants having higher affinity for the ErbB3 receptor by monovalent phage display.

Ballinger MD, Jones JT, Lofgren JA, Fairbrother WJ, Akita RW, Sliwkowski MX, Wells JA. Ballinger MD, et al. Among authors: akita rw. J Biol Chem. 1998 May 8;273(19):11675-84. doi: 10.1074/jbc.273.19.11675. J Biol Chem. 1998. PMID: 9565588 Free article.

7

A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2.

Schaefer G, Akita RW, Sliwkowski MX. Schaefer G, et al. Among authors: akita rw. J Biol Chem. 1999 Jan 8;274(2):859-66. doi: 10.1074/jbc.274.2.859. J Biol Chem. 1999. PMID: 9873025 Free article.

8

Binding specificities and affinities of egf domains for ErbB receptors.

Jones JT, Akita RW, Sliwkowski MX. Jones JT, et al. Among authors: akita rw. FEBS Lett. 1999 Mar 26;447(2-3):227-31. doi: 10.1016/s0014-5793(99)00283-5. FEBS Lett. 1999. PMID: 10214951 Free article.

9

Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells.

Aguilar Z, Akita RW, Finn RS, Ramos BL, Pegram MD, Kabbinavar FF, Pietras RJ, Pisacane P, Sliwkowski MX, Slamon DJ. Aguilar Z, et al. Among authors: akita rw. Oncogene. 1999 Oct 28;18(44):6050-62. doi: 10.1038/sj.onc.1202993. Oncogene. 1999. PMID: 10557094

10

A potential role for activated HER-2 in prostate cancer.

Agus DB, Akita RW, Fox WD, Lofgren JA, Higgins B, Maiese K, Scher HI, Sliwkowski MX. Agus DB, et al. Among authors: akita rw. Semin Oncol. 2000 Dec;27(6 Suppl 11):76-83; discussion 92-100. Semin Oncol. 2000. PMID: 11236032 Review.

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