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Substituted indole-2-carboxylates as in vivo potent antagonists acting as the strychnine-insensitive glycine binding site.
Di Fabio R, Capelli AM, Conti N, Cugola A, Donati D, Feriani A, Gastaldi P, Gaviraghi G, Hewkin CT, Micheli F, Missio A, Mugnaini M, Pecunioso A, Quaglia AM, Ratti E, Rossi L, Tedesco G, Trist DG, Reggiani A. Di Fabio R, et al. Among authors: quaglia am. J Med Chem. 1997 Mar 14;40(6):841-50. doi: 10.1021/jm960644a. J Med Chem. 1997. PMID: 9083472
Cycloalkyl indole-2-carboxylates as useful tools for mapping the "north-eastern" region of the glycine binding site associated with the NMDA receptor.
Micheli F, Di Fabio R, Capelli AM, Cugola A, Curcuruto O, Feriani A, Gastaldi P, Gaviraghi G, Marchioro C, Orlandi A, Pozzan A, Quaglia AM, Reggiani A, van Amsterdam F. Micheli F, et al. Among authors: quaglia am. Arch Pharm (Weinheim). 1999 Mar;332(3):73-80. doi: 10.1002/(sici)1521-4184(19993)332:3<73::aid-ardp73>3.0.co;2-5. Arch Pharm (Weinheim). 1999. PMID: 10228452