Pawson T - Search Results

1

Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins.

Howard PL, Chia MC, Del Rizzo S, Liu FF, Pawson T. Howard PL, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11267-72. doi: 10.1073/pnas.1934711100. Epub 2003 Sep 17. Proc Natl Acad Sci U S A. 2003. PMID: 13679576 Free PMC article.

2

Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages.

Kimura Y, Jones N, Klüppel M, Hirashima M, Tachibana K, Cohn JB, Wrana JL, Pawson T, Bernstein A. Kimura Y, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6015-20. doi: 10.1073/pnas.0305363101. Epub 2004 Apr 5. Proc Natl Acad Sci U S A. 2004. PMID: 15067126 Free PMC article.

3

Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases.

McGlade J, Cheng A, Pelicci G, Pelicci PG, Pawson T. McGlade J, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8869-73. doi: 10.1073/pnas.89.19.8869. Proc Natl Acad Sci U S A. 1992. PMID: 1409579 Free PMC article.

4

Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1.

Piao X, Paulson R, van der Geer P, Pawson T, Bernstein A. Piao X, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14665-9. doi: 10.1073/pnas.93.25.14665. Proc Natl Acad Sci U S A. 1996. PMID: 8962111 Free PMC article.

5

Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling.

Louria-Hayon I, Frelin C, Ruston J, Gish G, Jin J, Kofler MM, Lambert JP, Adissu HA, Milyavsky M, Herrington R, Minden MD, Dick JE, Gingras AC, Iscove NN, Pawson T. Louria-Hayon I, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20599-604. doi: 10.1073/pnas.1319665110. Epub 2013 Dec 2. Proc Natl Acad Sci U S A. 2013. PMID: 24297922 Free PMC article.

6

Nck adaptor proteins control the organization of neuronal circuits important for walking.

Fawcett JP, Georgiou J, Ruston J, Bladt F, Sherman A, Warner N, Saab BJ, Scott R, Roder JC, Pawson T. Fawcett JP, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20973-8. doi: 10.1073/pnas.0710316105. Epub 2007 Dec 18. Proc Natl Acad Sci U S A. 2007. PMID: 18093944 Free PMC article.

7

Src homology region 2 domains direct protein-protein interactions in signal transduction.

Moran MF, Koch CA, Anderson D, Ellis C, England L, Martin GS, Pawson T. Moran MF, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8622-6. doi: 10.1073/pnas.87.21.8622. Proc Natl Acad Sci U S A. 1990. PMID: 2236073 Free PMC article.

8

The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling.

Cheng AM, Negishi I, Anderson SJ, Chan AC, Bolen J, Loh DY, Pawson T. Cheng AM, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9797-801. doi: 10.1073/pnas.94.18.9797. Proc Natl Acad Sci U S A. 1997. PMID: 9275205 Free PMC article.

9

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.

van der Geer P, Wiley S, Gish GD, Lai VK, Stephens R, White MF, Kaplan D, Pawson T. van der Geer P, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):963-8. doi: 10.1073/pnas.93.3.963. Proc Natl Acad Sci U S A. 1996. PMID: 8577769 Free PMC article.

10

Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide.

Donaldson LW, Gish G, Pawson T, Kay LE, Forman-Kay JD. Donaldson LW, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14053-8. doi: 10.1073/pnas.212518799. Epub 2002 Oct 16. Proc Natl Acad Sci U S A. 2002. PMID: 12384576 Free PMC article.

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