Sawyer R - Search Results

1

A phase II trial of biochemical modulation using N-phosphonacetyl-L-aspartate, high-dose methotrexate, high-dose 5-fluorouracil, and leucovorin in patients with adenocarcinoma of unknown primary site.

Kelsen D, Martin DS, Colofiore J, Sawyer R, Coit D. Kelsen D, et al. Among authors: sawyer r. Cancer. 1992 Oct 1;70(7):1988-92. doi: 10.1002/1097-0142(19921001)70:7<1988::aid-cncr2820700730>3.0.co;2-k. Cancer. 1992. PMID: 1381991 Clinical Trial.

2

Effect of L-histidinol on the metabolism of 5-fluorouracil in the BALB/c x DBA/8 F1 murine tumor system.

Sawyer RC, Stolfi RL, Martin DS. Sawyer RC, et al. Cancer Res. 1988 Dec 1;48(23):6664-8. Cancer Res. 1988. PMID: 2460227

3

Phase I trial of N-(phosphonacetyl)-L-aspartate, methotrexate, and 5-fluorouracil with leucovorin rescue in patients with advanced cancer.

Kemeny N, Schneider A, Martin DS, Colofiore J, Sawyer RC, Derby S, Salvia B. Kemeny N, et al. Among authors: sawyer rc. Cancer Res. 1989 Aug 15;49(16):4636-9. Cancer Res. 1989. PMID: 2472883

4

Use of oral uridine as a substitute for parenteral uridine rescue of 5-fluorouracil therapy, with and without the uridine phosphorylase inhibitor 5-benzylacyclouridine.

Martin DS, Stolfi RL, Sawyer RC. Martin DS, et al. Among authors: sawyer rc. Cancer Chemother Pharmacol. 1989;24(1):9-14. doi: 10.1007/BF00254098. Cancer Chemother Pharmacol. 1989. PMID: 2720896

5

Improved therapeutic index with sequential N-phosphonacetyl-L-aspartate plus high-dose methotrexate plus high-dose 5-fluorouracil and appropriate rescue.

Martin DS, Stolfi RL, Sawyer RC, Spiegelman S, Young CW. Martin DS, et al. Among authors: sawyer rc. Cancer Res. 1983 Oct;43(10):4653-61. Cancer Res. 1983. PMID: 6603903

6

Uridine allows dose escalation of 5-fluorouracil when given with N-phosphonacetyl-L-aspartate, methotrexate, and leucovorin.

Seiter K, Kemeny N, Martin D, Schneider A, Williams L, Colofiore J, Sawyer R. Seiter K, et al. Among authors: sawyer r. Cancer. 1993 Mar 1;71(5):1875-81. doi: 10.1002/1097-0142(19930301)71:5<1875::aid-cncr2820710526>3.0.co;2-9. Cancer. 1993. PMID: 8448752

7

In vivo monitoring of changes in 5-fluorouracil metabolism induced by methotrexate measured by 19F NMR spectroscopy.

Koutcher JA, Sawyer RC, Kornblith AB, Stolfi RL, Martin DS, Devitt ML, Cowburn D, Young CW. Koutcher JA, et al. Among authors: sawyer rc. Magn Reson Med. 1991 May;19(1):113-23. doi: 10.1002/mrm.1910190111. Magn Reson Med. 1991. PMID: 2046526

8

Effect of uridine diphosphoglucose on levels of 5-phosphoribosyl pyrophosphate and uridine triphosphate in murine tissues.

Colofiore JR, Sawyer RC, Balis ME, Martin DS. Colofiore JR, et al. Among authors: sawyer rc. Pharm Res. 1989 Oct;6(10):863-6. doi: 10.1023/a:1015908505351. Pharm Res. 1989. PMID: 2481854

9

Inhibition by methotrexate of the stable incorporation of 5-fluorouracil into murine bone marrow DNA.

Sawyer RC, Stolfi RL, Martin DS, Balis ME. Sawyer RC, et al. Biochem Pharmacol. 1989 Jul 15;38(14):2305-11. doi: 10.1016/0006-2952(89)90470-x. Biochem Pharmacol. 1989. PMID: 2751696

10

Failure of L-histidinol to improve the therapeutic efficiency of 5-fluorouracil against murine breast tumors.

Stolfi RL, Sawyer RC, Martin DS. Stolfi RL, et al. Among authors: sawyer rc. Cancer Res. 1987 Jan 1;47(1):16-20. Cancer Res. 1987. PMID: 3791203

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