Halpert JR - Search Results

1

Role of residue 478 as a determinant of the substrate specificity of cytochrome P450 2B1.

He YA, Balfour CA, Kedzie KM, Halpert JR. He YA, et al. Among authors: halpert jr. Biochemistry. 1992 Sep 29;31(38):9220-6. doi: 10.1021/bi00153a015. Biochemistry. 1992. PMID: 1390709

2

Molecular basis for a functionally unique cytochrome P450IIB1 variant.

Kedzie KM, Balfour CA, Escobar GY, Grimm SW, He YA, Pepperl DJ, Regan JW, Stevens JC, Halpert JR. Kedzie KM, et al. Among authors: halpert jr. J Biol Chem. 1991 Nov 25;266(33):22515-21. J Biol Chem. 1991. PMID: 1718996 Free article.

3

Functional expression of mammalian cytochromes P450IIB in the yeast Saccharomyces cerevisiae.

Kedzie KM, Philpot RM, Halpert JR. Kedzie KM, et al. Among authors: halpert jr. Arch Biochem Biophys. 1991 Nov 15;291(1):176-86. doi: 10.1016/0003-9861(91)90121-x. Arch Biochem Biophys. 1991. PMID: 1929429

4

Escherichia coli expression of site-directed mutants of cytochrome P450 2B1 from six substrate recognition sites: substrate specificity and inhibitor selectivity studies.

He YQ, He YA, Halpert JR. He YQ, et al. Among authors: halpert jr. Chem Res Toxicol. 1995 Jun;8(4):574-9. doi: 10.1021/tx00046a011. Chem Res Toxicol. 1995. PMID: 7548737

5

Site-directed mutagenesis as a tool for molecular modeling of cytochrome P450 2B1.

Szklarz GD, He YA, Halpert JR. Szklarz GD, et al. Among authors: halpert jr. Biochemistry. 1995 Nov 7;34(44):14312-22. doi: 10.1021/bi00044a008. Biochemistry. 1995. PMID: 7578035

6

Escherichia coli expression and characterization of cytochromes P450 2B11, 2B1, and 2B5.

John GH, Hasler JA, He YA, Halpert JR. John GH, et al. Among authors: halpert jr. Arch Biochem Biophys. 1994 Nov 1;314(2):367-75. doi: 10.1006/abbi.1994.1455. Arch Biochem Biophys. 1994. PMID: 7979377

7

Site-directed mutagenesis of putative substrate recognition sites in cytochrome P450 2B11: importance of amino acid residues 114, 290, and 363 for substrate specificity.

Hasler JA, Harlow GR, Szklarz GD, John GH, Kedzie KM, Burnett VL, He YA, Kaminsky LS, Halpert JR. Hasler JA, et al. Among authors: halpert jr. Mol Pharmacol. 1994 Aug;46(2):338-45. Mol Pharmacol. 1994. PMID: 8078495

8

Role of residues 363 and 206 in conversion of cytochrome P450 2B1 from a steroid 16-hydroxylase to a 15 alpha-hydroxylase.

Luo Z, He YA, Halpert JR. Luo Z, et al. Among authors: halpert jr. Arch Biochem Biophys. 1994 Feb 15;309(1):52-7. doi: 10.1006/abbi.1994.1083. Arch Biochem Biophys. 1994. PMID: 8117113

9

Structural determinants of cytochrome P450 2B1 specificity: evidence for five substrate recognition sites.

He Y, Luo Z, Klekotka PA, Burnett VL, Halpert JR. He Y, et al. Among authors: halpert jr. Biochemistry. 1994 Apr 12;33(14):4419-24. doi: 10.1021/bi00180a040. Biochemistry. 1994. PMID: 8155660

10

Cloning, sequencing, and functional studies of phenobarbital-inducible forms of cytochrome P450 2B and 4B expressed in rabbit kidney.

Ryan R, Grimm SW, Kedzie KM, Halpert JR, Philpot RM. Ryan R, et al. Among authors: halpert jr. Arch Biochem Biophys. 1993 Aug 1;304(2):454-63. doi: 10.1006/abbi.1993.1375. Arch Biochem Biophys. 1993. PMID: 8346920

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