Güngör T - Search Results

1

Cardiotonic agents. Synthesis and cardiovascular properties of novel 2-arylbenzimidazoles and azabenzimidazoles.

Güngör T, Fouquet A, Teulon JM, Provost D, Cazes M, Cloarec A. Güngör T, et al. J Med Chem. 1992 Nov 13;35(23):4455-63. doi: 10.1021/jm00101a024. J Med Chem. 1992. PMID: 1447745

2

N6-substituted adenosine receptor agonists. Synthesis and pharmacological activity as potent antinociceptive agents.

Güngör T, Malabre P, Teulon JM, Camborde F, Meignen J, Hertz F, Virone-Oddos A, Caussade F, Cloarec A. Güngör T, et al. J Med Chem. 1994 Dec 9;37(25):4307-16. doi: 10.1021/jm00051a007. J Med Chem. 1994. PMID: 7996542

3

Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer.

Tokay E, Güngör T, Hacıoğlu N, Önder FC, Gülhan ÜG, Tok TT, Çelik A, Ay M, Köçkar F. Tokay E, et al. Among authors: gungor t. Eur J Med Chem. 2020 Feb 1;187:111937. doi: 10.1016/j.ejmech.2019.111937. Epub 2019 Dec 9. Eur J Med Chem. 2020. PMID: 31841727

4

New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects.

Güngör T, Ozleyen A, Yılmaz YB, Siyah P, Ay M, Durdağı S, Tumer TB. Güngör T, et al. Eur J Med Chem. 2021 Oct 5;221:113566. doi: 10.1016/j.ejmech.2021.113566. Epub 2021 May 24. Eur J Med Chem. 2021. PMID: 34077833

5

PRODRUGS FOR NITROREDUCTASE BASED CANCER THERAPY- 2: Novel amide/Ntr combinations targeting PC3 cancer cells.

Güngör T, Önder FC, Tokay E, Gülhan ÜG, Hacıoğlu N, Tok TT, Çelik A, Köçkar F, Ay M. Güngör T, et al. Eur J Med Chem. 2019 Jun 1;171:383-400. doi: 10.1016/j.ejmech.2019.03.035. Epub 2019 Mar 23. Eur J Med Chem. 2019. PMID: 30928710

6

Modification of existing antibiotics in the form of precursor prodrugs that can be subsequently activated by nitroreductases of the target pathogen.

Çelik A, Yetiş G, Ay M, Güngör T. Çelik A, et al. Among authors: gungor t. Bioorg Med Chem Lett. 2016 Aug 15;26(16):4057-60. doi: 10.1016/j.bmcl.2016.06.081. Epub 2016 Jun 28. Bioorg Med Chem Lett. 2016. PMID: 27390065

7

Biological evaluation and molecular docking studies of nitro benzamide derivatives with respect to in vitro anti-inflammatory activity.

Tumer TB, Onder FC, Ipek H, Gungor T, Savranoglu S, Tok TT, Celik A, Ay M. Tumer TB, et al. Among authors: gungor t. Int Immunopharmacol. 2017 Feb;43:129-139. doi: 10.1016/j.intimp.2016.12.009. Epub 2016 Dec 16. Int Immunopharmacol. 2017. PMID: 27988460

8

Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB.

Gungor T, Yetis G, Onder FC, Tokay E, Tok TT, Celik A, Ay M, Kockar F. Gungor T, et al. Med Chem. 2018;14(5):495-507. doi: 10.2174/1573406413666171129224424. Med Chem. 2018. PMID: 29189173

9

Prodrugs for nitroreductase based cancer therapy-4: Towards prostate cancer targeting: Synthesis of N-heterocyclic nitro prodrugs, Ssap-NtrB enzymatic activation and anticancer evaluation.

Güngör T, Tokay E, Güven Gülhan Ü, Hacıoğlu N, Çelik A, Köçkar F, Ay M. Güngör T, et al. Bioorg Chem. 2020 Dec;105:104450. doi: 10.1016/j.bioorg.2020.104450. Epub 2020 Nov 4. Bioorg Chem. 2020. PMID: 33189994

10

Microwave assisted, sequential two-step, one-pot synthesis of novel imidazo[1,2-a]pyrimidine containing tri/tetrasubstituted imidazole derivatives.

GÜngÖr T. GÜngÖr T. Turk J Chem. 2021 Feb 17;45(1):219-230. doi: 10.3906/kim-2009-40. eCollection 2021. Turk J Chem. 2021. PMID: 33679165 Free PMC article.

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