Liu H - Search Results

1

Virtual screening on natural products for discovering active compounds and target information.

Shen J, Xu X, Cheng F, Liu H, Luo X, Shen J, Chen K, Zhao W, Shen X, Jiang H. Shen J, et al. Among authors: liu h. Curr Med Chem. 2003 Nov;10(21):2327-42. doi: 10.2174/0929867033456729. Curr Med Chem. 2003. PMID: 14529345 Review.

2

Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: molecular docking and 3D QSAR analyses.

Liu H, Huang X, Shen J, Luo X, Li M, Xiong B, Chen G, Shen J, Yang Y, Jiang H, Chen K. Liu H, et al. J Med Chem. 2002 Oct 24;45(22):4816-27. doi: 10.1021/jm020089e. J Med Chem. 2002. PMID: 12383007

3

Structure-based discovery of potassium channel blockers from natural products: virtual screening and electrophysiological assay testing.

Liu H, Li Y, Song M, Tan X, Cheng F, Zheng S, Shen J, Luo X, Ji R, Yue J, Hu G, Jiang H, Chen K. Liu H, et al. Chem Biol. 2003 Nov;10(11):1103-13. doi: 10.1016/j.chembiol.2003.10.011. Chem Biol. 2003. PMID: 14652078

4

Discovering novel chemical inhibitors of human cyclophilin A: virtual screening, synthesis, and bioassay.

Li J, Chen J, Gui C, Zhang L, Qin Y, Xu Q, Zhang J, Liu H, Shen X, Jiang H. Li J, et al. Among authors: liu h. Bioorg Med Chem. 2006 Apr 1;14(7):2209-24. doi: 10.1016/j.bmc.2005.11.006. Epub 2005 Nov 22. Bioorg Med Chem. 2006. PMID: 16307882 Free PMC article.

5

Strategy for discovering chemical inhibitors of human cyclophilin a: focused library design, virtual screening, chemical synthesis and bioassay.

Li J, Zhang J, Chen J, Luo X, Zhu W, Shen J, Liu H, Shen X, Jiang H. Li J, et al. Among authors: liu h. J Comb Chem. 2006 May-Jun;8(3):326-37. doi: 10.1021/cc0501561. J Comb Chem. 2006. PMID: 16677001

6

Discovering potassium channel blockers from synthetic compound database by using structure-based virtual screening in conjunction with electrophysiological assay.

Liu H, Gao ZB, Yao Z, Zheng S, Li Y, Zhu W, Tan X, Luo X, Shen J, Chen K, Hu GY, Jiang H. Liu H, et al. J Med Chem. 2007 Jan 11;50(1):83-93. doi: 10.1021/jm060414o. J Med Chem. 2007. PMID: 17201412

7

Pyrazolidine-3,5-dione derivatives as potent non-steroidal agonists of farnesoid X receptor: virtual screening, synthesis, and biological evaluation.

Deng G, Li W, Shen J, Jiang H, Chen K, Liu H. Deng G, et al. Among authors: liu h. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5497-502. doi: 10.1016/j.bmcl.2008.09.027. Epub 2008 Sep 10. Bioorg Med Chem Lett. 2008. PMID: 18815030

8

Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.

He L, Zhang L, Liu X, Li X, Zheng M, Li H, Yu K, Chen K, Shen X, Jiang H, Liu H. He L, et al. Among authors: liu x, liu h. J Med Chem. 2009 Apr 23;52(8):2465-81. doi: 10.1021/jm8015602. J Med Chem. 2009. PMID: 19309082

9

Current strategies for the discovery of K+ channel modulators.

Ye D, Wang J, Yu K, Zhou Y, Jiang H, Chen K, Liu H. Ye D, et al. Among authors: liu h. Curr Top Med Chem. 2009;9(4):348-61. doi: 10.2174/156802609788317865. Curr Top Med Chem. 2009. PMID: 19442206 Review.

10

New p-methylsulfonamido phenylethylamine analogues as class III antiarrhythmic agents: design, synthesis, biological assay, and 3D-QSAR analysis.

Liu H, Ji M, Luo X, Shen J, Huang X, Hua W, Jiang H, Chen K. Liu H, et al. J Med Chem. 2002 Jul 4;45(14):2953-69. doi: 10.1021/jm010574u. J Med Chem. 2002. PMID: 12086482

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