Porteous DJ - Search Results

1

Transfection efficiency and toxicity following delivery of naked plasmid DNA and cationic lipid-DNA complexes to ovine lung segments.

Emerson M, Renwick L, Tate S, Rhind S, Milne E, Painter HA, Boyd AC, McLachlan G, Griesenbach U, Cheng SH, Gill DR, Hyde SC, Baker A, Alton EW, Porteous DJ, Collie DD. Emerson M, et al. Among authors: porteous dj. Mol Ther. 2003 Oct;8(4):646-53. doi: 10.1016/s1525-0016(03)00233-8. Mol Ther. 2003. PMID: 14529838 Free article.

2

Lung disease in the cystic fibrosis mouse exposed to bacterial pathogens.

Davidson DJ, Dorin JR, McLachlan G, Ranaldi V, Lamb D, Doherty C, Govan J, Porteous DJ. Davidson DJ, et al. Among authors: porteous dj. Nat Genet. 1995 Apr;9(4):351-7. doi: 10.1038/ng0495-351. Nat Genet. 1995. PMID: 7540910

3

Cystic fibrosis: prospects for therapy.

Porteous DJ, Alton EW. Porteous DJ, et al. Bioessays. 1993 Jul;15(7):485-6. doi: 10.1002/bies.950150708. Bioessays. 1993. PMID: 7691059 Review. No abstract available.

4

Bioelectric characteristics of exon 10 insertional cystic fibrosis mouse: comparison with humans.

Smith SN, Steel DM, Middleton PG, Munkonge FM, Geddes DM, Caplen NJ, Porteous DJ, Dorin JR, Alton EW. Smith SN, et al. Among authors: porteous dj. Am J Physiol. 1995 Feb;268(2 Pt 1):C297-307. doi: 10.1152/ajpcell.1995.268.2.C297. Am J Physiol. 1995. PMID: 7864068

5

Long-term survival of the exon 10 insertional cystic fibrosis mutant mouse is a consequence of low level residual wild-type Cftr gene expression.

Dorin JR, Stevenson BJ, Fleming S, Alton EW, Dickinson P, Porteous DJ. Dorin JR, et al. Among authors: porteous dj. Mamm Genome. 1994 Aug;5(8):465-72. doi: 10.1007/BF00369314. Mamm Genome. 1994. PMID: 7949729 Free article.

6

Evaluation in vitro and in vivo of cationic liposome-expression construct complexes for cystic fibrosis gene therapy.

McLachlan G, Davidson DJ, Stevenson BJ, Dickinson P, Davidson-Smith H, Dorin JR, Porteous DJ. McLachlan G, et al. Among authors: porteous dj. Gene Ther. 1995 Nov;2(9):614-22. Gene Ther. 1995. PMID: 8548550

7

A demonstration using mouse models that successful gene therapy for cystic fibrosis requires only partial gene correction.

Dorin JR, Farley R, Webb S, Smith SN, Farini E, Delaney SJ, Wainwright BJ, Alton EW, Porteous DJ. Dorin JR, et al. Among authors: porteous dj. Gene Ther. 1996 Sep;3(9):797-801. Gene Ther. 1996. PMID: 8875228

8

Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolisation.

Crook K, McLachlan G, Stevenson BJ, Porteous DJ. Crook K, et al. Among authors: porteous dj. Gene Ther. 1996 Sep;3(9):834-9. Gene Ther. 1996. PMID: 8875234

9

Laboratory and clinical studies in support of cystic fibrosis gene therapy using pCMV-CFTR-DOTAP.

McLachlan G, Ho LP, Davidson-Smith H, Samways J, Davidson H, Stevenson BJ, Carothers AD, Alton EW, Middleton PG, Smith SN, Kallmeyer G, Michaelis U, Seeber S, Naujoks K, Greening AP, Innes JA, Dorin JR, Porteous DJ. McLachlan G, et al. Among authors: porteous dj. Gene Ther. 1996 Dec;3(12):1113-23. Gene Ther. 1996. PMID: 8986438

10

Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.

Porteous DJ, Dorin JR, McLachlan G, Davidson-Smith H, Davidson H, Stevenson BJ, Carothers AD, Wallace WA, Moralee S, Hoenes C, Kallmeyer G, Michaelis U, Naujoks K, Ho LP, Samways JM, Imrie M, Greening AP, Innes JA. Porteous DJ, et al. Gene Ther. 1997 Mar;4(3):210-8. doi: 10.1038/sj.gt.3300390. Gene Ther. 1997. PMID: 9135734 Clinical Trial.

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