Lawrence JC - Search Results

1

Modulation of the protein kinase activity of mTOR.

Lawrence JC, Lin TA, McMahon LP, Choi KM. Lawrence JC, et al. Curr Top Microbiol Immunol. 2004;279:199-213. doi: 10.1007/978-3-642-18930-2_12. Curr Top Microbiol Immunol. 2004. PMID: 14560959 Review.

2

The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin.

McMahon LP, Choi KM, Lin TA, Abraham RT, Lawrence JC Jr. McMahon LP, et al. Among authors: lawrence jc jr. Mol Cell Biol. 2002 Nov;22(21):7428-38. doi: 10.1128/MCB.22.21.7428-7438.2002. Mol Cell Biol. 2002. PMID: 12370290 Free PMC article.

3

Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor.

Choi KM, McMahon LP, Lawrence JC Jr. Choi KM, et al. Among authors: lawrence jc jr. J Biol Chem. 2003 May 30;278(22):19667-73. doi: 10.1074/jbc.M301142200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665511 Free article.

4

Farnesylthiosalicylic acid inhibits mammalian target of rapamycin (mTOR) activity both in cells and in vitro by promoting dissociation of the mTOR-raptor complex.

McMahon LP, Yue W, Santen RJ, Lawrence JC Jr. McMahon LP, et al. Among authors: lawrence jc jr. Mol Endocrinol. 2005 Jan;19(1):175-83. doi: 10.1210/me.2004-0305. Epub 2004 Sep 30. Mol Endocrinol. 2005. PMID: 15459249

5

Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes.

Haystead TA, Haystead CM, Hu C, Lin TA, Lawrence JC Jr. Haystead TA, et al. Among authors: lawrence jc jr. J Biol Chem. 1994 Sep 16;269(37):23185-91. J Biol Chem. 1994. PMID: 8083223 Free article.

6

Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes.

Lin TA, Lawrence JC Jr. Lin TA, et al. Among authors: lawrence jc jr. J Biol Chem. 1996 Nov 22;271(47):30199-204. doi: 10.1074/jbc.271.47.30199. J Biol Chem. 1996. PMID: 8939971 Free article.

7

PHAS proteins as mediators of the actions of insulin, growth factors and cAMP on protein synthesis and cell proliferation.

Lawrence JC Jr, Fadden P, Haystead TA, Lin TA. Lawrence JC Jr, et al. Adv Enzyme Regul. 1997;37:239-67. doi: 10.1016/s0065-2571(96)00016-7. Adv Enzyme Regul. 1997. PMID: 9381973 Review.

8

Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies.

Mothe-Satney I, Brunn GJ, McMahon LP, Capaldo CT, Abraham RT, Lawrence JC Jr. Mothe-Satney I, et al. Among authors: lawrence jc jr. J Biol Chem. 2000 Oct 27;275(43):33836-43. doi: 10.1074/jbc.M006005200. J Biol Chem. 2000. PMID: 10942774 Free article.

9

Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity.

Kumar A, Harris TE, Keller SR, Choi KM, Magnuson MA, Lawrence JC Jr. Kumar A, et al. Among authors: lawrence jc jr. Mol Cell Biol. 2008 Jan;28(1):61-70. doi: 10.1128/MCB.01405-07. Epub 2007 Oct 29. Mol Cell Biol. 2008. PMID: 17967879 Free PMC article.

10

Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway.

Lin TA, Kong X, Saltiel AR, Blackshear PJ, Lawrence JC Jr. Lin TA, et al. Among authors: lawrence jc jr. J Biol Chem. 1995 Aug 4;270(31):18531-8. doi: 10.1074/jbc.270.31.18531. J Biol Chem. 1995. PMID: 7629182 Free article.

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