McMahon LP - Search Results

1

Modulation of the protein kinase activity of mTOR.

Lawrence JC, Lin TA, McMahon LP, Choi KM. Lawrence JC, et al. Among authors: mcmahon lp. Curr Top Microbiol Immunol. 2004;279:199-213. doi: 10.1007/978-3-642-18930-2_12. Curr Top Microbiol Immunol. 2004. PMID: 14560959 Review.

2

Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies.

Mothe-Satney I, Brunn GJ, McMahon LP, Capaldo CT, Abraham RT, Lawrence JC Jr. Mothe-Satney I, et al. Among authors: mcmahon lp. J Biol Chem. 2000 Oct 27;275(43):33836-43. doi: 10.1074/jbc.M006005200. J Biol Chem. 2000. PMID: 10942774 Free article.

3

The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin.

McMahon LP, Choi KM, Lin TA, Abraham RT, Lawrence JC Jr. McMahon LP, et al. Mol Cell Biol. 2002 Nov;22(21):7428-38. doi: 10.1128/MCB.22.21.7428-7438.2002. Mol Cell Biol. 2002. PMID: 12370290 Free PMC article.

4

Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor.

Choi KM, McMahon LP, Lawrence JC Jr. Choi KM, et al. Among authors: mcmahon lp. J Biol Chem. 2003 May 30;278(22):19667-73. doi: 10.1074/jbc.M301142200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665511 Free article.

5

Farnesylthiosalicylic acid inhibits mammalian target of rapamycin (mTOR) activity both in cells and in vitro by promoting dissociation of the mTOR-raptor complex.

McMahon LP, Yue W, Santen RJ, Lawrence JC Jr. McMahon LP, et al. Mol Endocrinol. 2005 Jan;19(1):175-83. doi: 10.1210/me.2004-0305. Epub 2004 Sep 30. Mol Endocrinol. 2005. PMID: 15459249

6

mTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease.

Norambuena A, Wallrabe H, McMahon L, Silva A, Swanson E, Khan SS, Baerthlein D, Kodis E, Oddo S, Mandell JW, Bloom GS. Norambuena A, et al. Alzheimers Dement. 2017 Feb;13(2):152-167. doi: 10.1016/j.jalz.2016.08.015. Epub 2016 Sep 29. Alzheimers Dement. 2017. PMID: 27693185 Free PMC article.

7

Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons: EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND "OFF-PATHWAY" CELLULAR MECHANISMS.

Yap CC, Digilio L, McMahon L, Roszkowska M, Bott CJ, Kruczek K, Winckler B. Yap CC, et al. J Biol Chem. 2016 Dec 23;291(52):26613-26626. doi: 10.1074/jbc.M116.760777. Epub 2016 Oct 31. J Biol Chem. 2016. PMID: 27799303 Free PMC article.

8

Extracellular Tau Oligomers Induce Invasion of Endogenous Tau into the Somatodendritic Compartment and Axonal Transport Dysfunction.

Swanson E, Breckenridge L, McMahon L, Som S, McConnell I, Bloom GS. Swanson E, et al. J Alzheimers Dis. 2017;58(3):803-820. doi: 10.3233/JAD-170168. J Alzheimers Dis. 2017. PMID: 28482642 Free PMC article.

9

Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes.

Yap CC, Digilio L, McMahon LP, Garcia ADR, Winckler B. Yap CC, et al. Among authors: mcmahon lp. J Cell Biol. 2018 Sep 3;217(9):3141-3159. doi: 10.1083/jcb.201711039. Epub 2018 Jun 15. J Cell Biol. 2018. PMID: 29907658 Free PMC article.

10

Dynein Is Required for Rab7-Dependent Endosome Maturation, Retrograde Dendritic Transport, and Degradation.

Yap CC, Digilio L, McMahon LP, Wang T, Winckler B. Yap CC, et al. Among authors: mcmahon lp. J Neurosci. 2022 Jun 1;42(22):4415-4434. doi: 10.1523/JNEUROSCI.2530-21.2022. Epub 2022 Apr 26. J Neurosci. 2022. PMID: 35474277 Free PMC article.

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