Kavathas P - Search Results

1

Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement.

Kerry SE, Buslepp J, Cramer LA, Maile R, Hensley LL, Nielsen AI, Kavathas P, Vilen BJ, Collins EJ, Frelinger JA. Kerry SE, et al. Among authors: kavathas p. J Immunol. 2003 Nov 1;171(9):4493-503. doi: 10.4049/jimmunol.171.9.4493. J Immunol. 2003. PMID: 14568922 Free PMC article.

2

Comparison of the roles of CD8 alpha alpha and CD8 alpha beta in interaction with MHC class I.

Sun J, Kavathas PB. Sun J, et al. Among authors: kavathas pb. J Immunol. 1997 Dec 15;159(12):6077-82. J Immunol. 1997. PMID: 9550407

3

Molecular basis for the high affinity interaction between the thymic leukemia antigen and the CD8alphaalpha molecule.

Attinger A, Devine L, Wang-Zhu Y, Martin D, Wang JH, Reinherz EL, Kronenberg M, Cheroutre H, Kavathas P. Attinger A, et al. Among authors: kavathas p. J Immunol. 2005 Mar 15;174(6):3501-7. doi: 10.4049/jimmunol.174.6.3501. J Immunol. 2005. PMID: 15749886

4

Mapping the binding site on CD8 beta for MHC class I reveals mutants with enhanced binding.

Devine L, Thakral D, Nag S, Dobbins J, Hodsdon ME, Kavathas PB. Devine L, et al. J Immunol. 2006 Sep 15;177(6):3930-8. doi: 10.4049/jimmunol.177.6.3930. J Immunol. 2006. PMID: 16951356

5

Orientation of the Ig domains of CD8 alpha beta relative to MHC class I.

Devine L, Sun J, Barr MR, Kavathas PB. Devine L, et al. Among authors: kavathas pb. J Immunol. 1999 Jan 15;162(2):846-51. J Immunol. 1999. PMID: 9916707

6

The complementarity-determining region-like loops of CD8 alpha interact differently with beta 2-microglobulin of the class I molecules H-2Kb and thymic leukemia antigen, while similarly with their alpha 3 domains.

Devine L, Rogozinski L, Naidenko OV, Cheroutre H, Kavathas PB. Devine L, et al. J Immunol. 2002 Apr 15;168(8):3881-6. doi: 10.4049/jimmunol.168.8.3881. J Immunol. 2002. PMID: 11937542

7

Human CD8 beta, but not mouse CD8 beta, can be expressed in the absence of CD8 alpha as a beta beta homodimer.

Devine L, Kieffer LJ, Aitken V, Kavathas PB. Devine L, et al. Among authors: kavathas pb. J Immunol. 2000 Jan 15;164(2):833-8. doi: 10.4049/jimmunol.164.2.833. J Immunol. 2000. PMID: 10623829

8

Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination.

Thakral D, Dobbins J, Devine L, Kavathas PB. Thakral D, et al. J Immunol. 2008 Jun 1;180(11):7431-42. doi: 10.4049/jimmunol.180.11.7431. J Immunol. 2008. PMID: 18490743

9

CD8 binding to MHC class I molecules is influenced by T cell maturation and glycosylation.

Daniels MA, Devine L, Miller JD, Moser JM, Lukacher AE, Altman JD, Kavathas P, Hogquist KA, Jameson SC. Daniels MA, et al. Among authors: kavathas p. Immunity. 2001 Dec;15(6):1051-61. doi: 10.1016/s1074-7613(01)00252-7. Immunity. 2001. PMID: 11754824 Free article.

10

Location of the epitope for an anti-CD8alpha antibody 53.6.7 which enhances CD8alpha-MHC class I interaction indicates antibody stabilization of a higher affinity CD8 conformation.

Devine L, Hodsdon ME, Daniels MA, Jameson SC, Kavathas PB. Devine L, et al. Immunol Lett. 2004 May 15;93(2-3):123-30. doi: 10.1016/j.imlet.2004.02.002. Immunol Lett. 2004. PMID: 15158607

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