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Design, synthesis, and biological activity of methoctramine-related tetraamines bearing an 11-acetyl-5,11-dihydro-6H-pyrido[2,3-b][1,4] benzodiazepin-6-one moiety: structural requirements for optimum occupancy of muscarinic receptor subtypes as revealed by symmetrical and unsymmetrical polyamines.
Minarini A, Bolognesi ML, Budriesi R, Canossa M, Chiarini A, Spampinato S, Melchiorre C. Minarini A, et al. J Med Chem. 1994 Sep 30;37(20):3363-72. doi: 10.1021/jm00046a021. J Med Chem. 1994. PMID: 7932564
Synthesis and biological activity of some methoctramine-related tetraamines bearing a 11-acetyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]-benzodiazepin-6-one moiety as antimuscarinics: a second generation of highly selective M2 muscarinic receptor antagonists.
Melchiorre C, Bolognesi ML, Chiarini A, Minarini A, Spampinato S. Melchiorre C, et al. Among authors: minarini a. J Med Chem. 1993 Nov 12;36(23):3734-7. doi: 10.1021/jm00075a032. J Med Chem. 1993. PMID: 8246244 No abstract available.
113 results