Storr RC - Search Results

1

Isoquine and related amodiaquine analogues: a new generation of improved 4-aminoquinoline antimalarials.

O'Neill PM, Mukhtar A, Stocks PA, Randle LE, Hindley S, Ward SA, Storr RC, Bickley JF, O'Neil IA, Maggs JL, Hughes RH, Winstanley PA, Bray PG, Park BK. O'Neill PM, et al. Among authors: storr rc. J Med Chem. 2003 Nov 6;46(23):4933-45. doi: 10.1021/jm030796n. J Med Chem. 2003. PMID: 14584944

2

Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues.

Hindley S, Ward SA, Storr RC, Searle NL, Bray PG, Park BK, Davies J, O'Neill PM. Hindley S, et al. Among authors: storr rc. J Med Chem. 2002 Feb 28;45(5):1052-63. doi: 10.1021/jm0109816. J Med Chem. 2002. PMID: 11855985

3

The effect of fluorine substitution on the metabolism and antimalarial activity of amodiaquine.

O'Neill PM, Harrison AC, Storr RC, Hawley SR, Ward SA, Park BK. O'Neill PM, et al. Among authors: storr rc. J Med Chem. 1994 Apr 29;37(9):1362-70. doi: 10.1021/jm00035a017. J Med Chem. 1994. PMID: 8176713

4

Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of benzylamino and alkylamino ether analogues of artemisinin.

O'Neill PM, Bishop LP, Storr RC, Hawley SR, Maggs JL, Ward SA, Park BK. O'Neill PM, et al. Among authors: storr rc. J Med Chem. 1996 Oct 25;39(22):4511-4. doi: 10.1021/jm9604944. J Med Chem. 1996. PMID: 8893847

5

Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues.

O'Neill PM, Willock DJ, Hawley SR, Bray PG, Storr RC, Ward SA, Park BK. O'Neill PM, et al. Among authors: storr rc. J Med Chem. 1997 Feb 14;40(4):437-48. doi: 10.1021/jm960370r. J Med Chem. 1997. PMID: 9046333

6

Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether.

O'Neill PM, Searle NL, Kan KW, Storr RC, Maggs JL, Ward SA, Raynes K, Park BK. O'Neill PM, et al. Among authors: storr rc. J Med Chem. 1999 Dec 30;42(26):5487-93. doi: 10.1021/jm9903545. J Med Chem. 1999. PMID: 10639291

7

The effect of chemical substitution on the metabolic activation, metabolic detoxication, and pharmacological activity of amodiaquine in the mouse.

Ruscoe JE, Jewell H, Maggs JL, O'Neill PM, Storr RC, Ward SA, Park BK. Ruscoe JE, et al. Among authors: storr rc. J Pharmacol Exp Ther. 1995 Apr;273(1):393-404. J Pharmacol Exp Ther. 1995. PMID: 7714794

8

The effect of fluorine substitution on the physicochemical properties and the analgesic activity of paracetamol.

Barnard S, Storr RC, O'Neill PM, Park BK. Barnard S, et al. Among authors: storr rc. J Pharm Pharmacol. 1993 Aug;45(8):736-44. doi: 10.1111/j.2042-7158.1993.tb07099.x. J Pharm Pharmacol. 1993. PMID: 7901373

9

Biomimetic Fe(II)-mediated degradation of arteflene (Ro-42-1611). The first EPR spin-trapping evidence for the previously postulated secondary carbon-centered cyclohexyl radical.

O'Neill PM, Bishop LP, Searle NL, Maggs JL, Storr RC, Ward SA, Park BK, Mabbs F. O'Neill PM, et al. Among authors: storr rc. J Org Chem. 2000 Mar 10;65(5):1578-82. doi: 10.1021/jo991585m. J Org Chem. 2000. PMID: 10814129 No abstract available.

10

An investigation into the haematological toxicity of structural analogues of dapsone in-vivo and in-vitro.

Coleman MD, Tingle MD, Hussain F, Storr RC, Park BK. Coleman MD, et al. Among authors: storr rc. J Pharm Pharmacol. 1991 Nov;43(11):779-84. doi: 10.1111/j.2042-7158.1991.tb03481.x. J Pharm Pharmacol. 1991. PMID: 1686906

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