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Stress induces mitochondria-mediated apoptosis independent of SAPK/JNK activation in embryonic stem cells.
Nishitai G, Shimizu N, Negishi T, Kishimoto H, Nakagawa K, Kitagawa D, Watanabe T, Momose H, Ohata S, Tanemura S, Asaka S, Kubota J, Saito R, Yoshida H, Mak TW, Wada T, Penninger JM, Azuma N, Nishina H, Katada T. Nishitai G, et al. Among authors: mak tw. J Biol Chem. 2004 Jan 16;279(3):1621-6. doi: 10.1074/jbc.M310335200. Epub 2003 Oct 29. J Biol Chem. 2004. PMID: 14585831 Free article.
SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis.
Watanabe T, Nakagawa K, Ohata S, Kitagawa D, Nishitai G, Seo J, Tanemura S, Shimizu N, Kishimoto H, Wada T, Aoki J, Arai H, Iwatsubo T, Mochita M, Watanabe T, Satake M, Ito Y, Matsuyama T, Mak TW, Penninger JM, Nishina H, Katada T. Watanabe T, et al. Among authors: mak tw. Dev Biol. 2002 Oct 15;250(2):332-47. Dev Biol. 2002. PMID: 12376107 Free article.
The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells.
Sasaki T, Wada T, Kishimoto H, Irie-Sasaki J, Matsumoto G, Goto T, Yao Z, Wakeham A, Mak TW, Suzuki A, Cho SK, Zuniga-Pflucker JC, Oliveira-dos-Santos AJ, Katada T, Nishina H, Penninger JM. Sasaki T, et al. Among authors: mak tw. J Exp Med. 2001 Sep 17;194(6):757-68. doi: 10.1084/jem.194.6.757. J Exp Med. 2001. PMID: 11560992 Free PMC article.
Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.
Nishina H, Bachmann M, Oliveira-dos-Santos AJ, Kozieradzki I, Fischer KD, Odermatt B, Wakeham A, Shahinian A, Takimoto H, Bernstein A, Mak TW, Woodgett JR, Ohashi PS, Penninger JM. Nishina H, et al. Among authors: mak tw. J Exp Med. 1997 Sep 15;186(6):941-53. doi: 10.1084/jem.186.6.941. J Exp Med. 1997. PMID: 9294148 Free PMC article.
1,086 results