De Souza DP - Search Results

1

Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling.

Fairlie WD, Uboldi AD, McCoubrie JE, Wang CC, Lee EF, Yao S, De Souza DP, Mifsud S, Metcalf D, Nicola NA, Norton RS, Baca M. Fairlie WD, et al. Among authors: de souza dp. J Biol Chem. 2004 Jan 16;279(3):2125-34. doi: 10.1074/jbc.M310103200. Epub 2003 Oct 29. J Biol Chem. 2004. PMID: 14585833 Free article.

2

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130.

Nicholson SE, De Souza D, Fabri LJ, Corbin J, Willson TA, Zhang JG, Silva A, Asimakis M, Farley A, Nash AD, Metcalf D, Hilton DJ, Nicola NA, Baca M. Nicholson SE, et al. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6493-8. doi: 10.1073/pnas.100135197. Proc Natl Acad Sci U S A. 2000. PMID: 10829066 Free PMC article.

3

SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.

Krebs DL, Uren RT, Metcalf D, Rakar S, Zhang JG, Starr R, De Souza DP, Hanzinikolas K, Eyles J, Connolly LM, Simpson RJ, Nicola NA, Nicholson SE, Baca M, Hilton DJ, Alexander WS. Krebs DL, et al. Among authors: de souza dp. Mol Cell Biol. 2002 Jul;22(13):4567-78. doi: 10.1128/MCB.22.13.4567-4578.2002. Mol Cell Biol. 2002. PMID: 12052866 Free PMC article.

4

SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities.

De Souza D, Fabri LJ, Nash A, Hilton DJ, Nicola NA, Baca M. De Souza D, et al. Biochemistry. 2002 Jul 23;41(29):9229-36. doi: 10.1021/bi0259507. Biochemistry. 2002. PMID: 12119038

5

A fusion protein system for the recombinant production of short disulfide-containing peptides.

Fairlie WD, Uboldi AD, De Souza DP, Hemmings GJ, Nicola NA, Baca M. Fairlie WD, et al. Among authors: de souza dp. Protein Expr Purif. 2002 Oct;26(1):171-8. doi: 10.1016/s1046-5928(02)00521-1. Protein Expr Purif. 2002. PMID: 12356485

6

Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2.

Fairlie WD, De Souza D, Nicola NA, Baca M. Fairlie WD, et al. Biochem J. 2003 Jun 1;372(Pt 2):495-502. doi: 10.1042/BJ20030104. Biochem J. 2003. PMID: 12593670 Free PMC article.

7

Direct production of proteins with N-terminal cysteine for site-specific conjugation.

Gentle IE, De Souza DP, Baca M. Gentle IE, et al. Among authors: de souza dp. Bioconjug Chem. 2004 May-Jun;15(3):658-63. doi: 10.1021/bc049965o. Bioconjug Chem. 2004. PMID: 15149194

8

Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain.

Babon JJ, Yao S, DeSouza DP, Harrison CF, Fabri LJ, Liepinsh E, Scrofani SD, Baca M, Norton RS. Babon JJ, et al. FEBS J. 2005 Dec;272(23):6120-30. doi: 10.1111/j.1742-4658.2005.05010.x. FEBS J. 2005. PMID: 16302975 Free article.

9

The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.

Babon JJ, McManus EJ, Yao S, DeSouza DP, Mielke LA, Sprigg NS, Willson TA, Hilton DJ, Nicola NA, Baca M, Nicholson SE, Norton RS. Babon JJ, et al. Mol Cell. 2006 Apr 21;22(2):205-16. doi: 10.1016/j.molcel.2006.03.024. Mol Cell. 2006. PMID: 16630890 Free article.

10

Cord Blood CD8⁺ T Cells Have a Natural Propensity to Express IL-4 in a Fatty Acid Metabolism and Caspase Activation-Dependent Manner.

Zhang Y, Maksimovic J, Huang B, De Souza DP, Naselli G, Chen H, Zhang L, Weng K, Liang H, Xu Y, Wentworth JM, Huntington ND, Oshlack A, Gong S, Kallies A, Vuillermin P, Yang M, Harrison LC. Zhang Y, et al. Among authors: de souza dp. Front Immunol. 2018 Apr 25;9:879. doi: 10.3389/fimmu.2018.00879. eCollection 2018. Front Immunol. 2018. PMID: 29922282 Free PMC article.

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