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Dihydroceramide desaturase activity is modulated by oxidative stress.
Idkowiak-Baldys J, Apraiz A, Li L, Rahmaniyan M, Clarke CJ, Kraveka JM, Asumendi A, Hannun YA. Idkowiak-Baldys J, et al. Among authors: li l. Biochem J. 2010 Mar 29;427(2):265-74. doi: 10.1042/BJ20091589. Biochem J. 2010. PMID: 20105137 Free PMC article.
Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation.
Separovic D, Breen P, Boppana NB, Van Buren E, Joseph N, Kraveka JM, Rahmaniyan M, Li L, Gudz TI, Bielawska A, Bai A, Bielawski J, Pierce JS, Korbelik M. Separovic D, et al. Among authors: li l. Int J Oncol. 2013 Dec;43(6):2064-72. doi: 10.3892/ijo.2013.2132. Epub 2013 Oct 9. Int J Oncol. 2013. PMID: 24126464 Free PMC article.
Adaptive changes in tumor cells in response to reductive stress.
Zhang L, Zhang J, Ye ZW, Muhammad A, Li L, Culpepper JW, Townsend DM, Tew KD. Zhang L, et al. Among authors: li l. Biochem Pharmacol. 2024 Jan;219:115929. doi: 10.1016/j.bcp.2023.115929. Epub 2023 Nov 22. Biochem Pharmacol. 2024. PMID: 38000559 Free PMC article.
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