Jacob RJ - Search Results

1

Effects of recurrent antecedent hypoglycaemia and chronic hyperglycaemia on brainstem extra-cellular glucose concentrations during acute hypoglycaemia in conscious diabetic BB rats.

McCrimmon RJ, Jacob RJ, Fan X, McNay EC, Sherwin RS. McCrimmon RJ, et al. Among authors: jacob rj. Diabetologia. 2003 Dec;46(12):1658-61. doi: 10.1007/s00125-003-1231-4. Epub 2003 Nov 5. Diabetologia. 2003. PMID: 14600813

2

Metabolic effects of IGF-I and insulin in spontaneously diabetic BB/w rats.

Jacob RJ, Sherwin RS, Bowen L, Fryburg D, Fagin KD, Tamborlane WV, Shulman GI. Jacob RJ, et al. Am J Physiol. 1991 Feb;260(2 Pt 1):E262-8. doi: 10.1152/ajpendo.1991.260.2.E262. Am J Physiol. 1991. PMID: 1996629

3

Brainstem dysfunction is provoked by a less pronounced hypoglycemic stimulus in diabetic BB rats.

Jacob RJ, Weber AB, Dziura J, Morgen J, Sherwin RS. Jacob RJ, et al. Diabetes. 1995 Aug;44(8):900-5. doi: 10.2337/diab.44.8.900. Diabetes. 1995. PMID: 7621994

4

Time course of the defective alpha-cell response to hypoglycemia in diabetic BB rats.

Jacob RJ, Dziura J, Morgen JP, Shulman GI, Sherwin RS. Jacob RJ, et al. Metabolism. 1996 Nov;45(11):1422-6. doi: 10.1016/s0026-0495(96)90125-0. Metabolism. 1996. PMID: 8931649 Free article.

5

Effects of recurrent hypoglycemia on brainstem function in diabetic BB rats: protective adaptation during acute hypoglycemia.

Jacob RJ, Dziura J, Blumberg M, Morgen JP, Sherwin RS. Jacob RJ, et al. Diabetes. 1999 Jan;48(1):141-5. doi: 10.2337/diabetes.48.1.141. Diabetes. 1999. PMID: 9892235

6

AICAR and phlorizin reverse the hypoglycemia-specific defect in glucagon secretion in the diabetic BB rat.

McCrimmon RJ, Evans ML, Jacob RJ, Fan X, Zhu Y, Shulman GI, Sherwin RS. McCrimmon RJ, et al. Among authors: jacob rj. Am J Physiol Endocrinol Metab. 2002 Nov;283(5):E1076-83. doi: 10.1152/ajpendo.00195.2002. Am J Physiol Endocrinol Metab. 2002. PMID: 12376337 Free article.

7

Brain glucose levels are elevated in chronically hyperglycemic diabetic rats: no evidence for protective adaptation by the blood brain barrier.

Jacob RJ, Fan X, Evans ML, Dziura J, Sherwin RS. Jacob RJ, et al. Metabolism. 2002 Dec;51(12):1522-4. doi: 10.1053/meta.2002.36347. Metabolism. 2002. PMID: 12489061

8

Role of corticotrophin-releasing hormone in the impairment of counterregulatory responses to hypoglycemia.

Flanagan DE, Keshavarz T, Evans ML, Flanagan S, Fan X, Jacob RJ, Sherwin RS. Flanagan DE, et al. Among authors: jacob rj. Diabetes. 2003 Mar;52(3):605-13. doi: 10.2337/diabetes.52.3.605. Diabetes. 2003. PMID: 12606499

9

Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus.

McCrimmon RJ, Fan X, Ding Y, Zhu W, Jacob RJ, Sherwin RS. McCrimmon RJ, et al. Among authors: jacob rj. Diabetes. 2004 Aug;53(8):1953-8. doi: 10.2337/diabetes.53.8.1953. Diabetes. 2004. PMID: 15277372

10

Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses.

Evans ML, McCrimmon RJ, Flanagan DE, Keshavarz T, Fan X, McNay EC, Jacob RJ, Sherwin RS. Evans ML, et al. Among authors: jacob rj. Diabetes. 2004 Oct;53(10):2542-51. doi: 10.2337/diabetes.53.10.2542. Diabetes. 2004. PMID: 15448082

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