Cosman M - Search Results

1

Solution structure of an O6-[4-oxo-4-(3-pyridyl)butyl]guanine adduct in an 11 mer DNA duplex: evidence for formation of a base triplex.

Peterson LA, Vu C, Hingerty BE, Broyde S, Cosman M. Peterson LA, et al. Among authors: cosman m. Biochemistry. 2003 Nov 18;42(45):13134-44. doi: 10.1021/bi035217v. Biochemistry. 2003. PMID: 14609323

2

Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer.

de los Santos C, Cosman M, Hingerty BE, Ibanez V, Margulis LA, Geacintov NE, Broyde S, Patel DJ. de los Santos C, et al. Among authors: cosman m. Biochemistry. 1992 Jun 16;31(23):5245-52. doi: 10.1021/bi00138a002. Biochemistry. 1992. PMID: 1606148

3

Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction.

Cosman M, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1995 Nov 21;34(46):15334-50. doi: 10.1021/bi00046a043. Biochemistry. 1995. PMID: 7578150

4

Solution conformation of [AF]dG opposite a -1 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified Syn guanine into the major groove.

Mao B, Cosman M, Hingerty BE, Broyde S, Patel DJ. Mao B, et al. Among authors: cosman m. Biochemistry. 1995 May 9;34(18):6226-38. doi: 10.1021/bi00018a027. Biochemistry. 1995. PMID: 7742328

5

Solution conformation of the (-)-trans-anti-5-methylchrysene-dG adduct opposite dC in a DNA duplex: DNA bending associated with wedging of the methyl group of 5-methylchrysene to the 3'-side of the modification site.

Cosman M, Xu R, Hingerty BE, Amin S, Harvey RG, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1995 May 9;34(18):6247-60. doi: 10.1021/bi00018a029. Biochemistry. 1995. PMID: 7742330

6

Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans-anti-[BPh]dA opposite dT stereoisomer.

Cosman M, Laryea A, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1995 Jan 31;34(4):1295-307. doi: 10.1021/bi00004a024. Biochemistry. 1995. PMID: 7827077

The current observation that the (-)-trans-anti-[BPh]dA positioned opposite dT intercalates to the 3'-side of the intact modified base pair contrasts with our previous demonstration that the stereoisomeric (+)-trans-anti-[BPh]dA adduct positioned opposite dT intercalates to the 5 …

The current observation that the (-)-trans-anti-[BPh]dA positioned opposite dT intercalates to the 3'-side of the intact modified base pair …

7

Solution conformation of the (+)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the major groove.

Cosman M, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1994 Sep 27;33(38):11507-17. doi: 10.1021/bi00204a013. Biochemistry. 1994. PMID: 7918364

This solution structure of the (+)-trans-anti-[BP]dG.del 11-mer duplex where the pyrene ring intercalates into the helix with displacement of the modified deoxyguanosine into the major groove strikingly contrasts with our previous study on the (+)-trans-anti-[BP]dG.dC 11-mer dupl …

This solution structure of the (+)-trans-anti-[BP]dG.del 11-mer duplex where the pyrene ring intercalates into the helix with displacement o …

8

Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.

Cosman M, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1994 Sep 27;33(38):11518-27. doi: 10.1021/bi00204a014. Biochemistry. 1994. PMID: 7918365

The solution structure of the (+)-cis-anti-[BP]dG adduct positioned opposite a deletion site reported in this study is similar to the corresponding structure of the same adduct positioned opposite dC reported previously [Cosman, M., de los Santos, C., Fiala, R., Hin …

The solution structure of the (+)-cis-anti-[BP]dG adduct positioned opposite a deletion site reported in this study is similar to the corres …

9

Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair.

Cosman M, Fiala R, Hingerty BE, Laryea A, Lee H, Harvey RG, Amin S, Geacintov NE, Broyde S, Patel D. Cosman M, et al. Biochemistry. 1993 Nov 23;32(46):12488-97. doi: 10.1021/bi00097a029. Biochemistry. 1993. PMID: 8241140

10

Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine.

Cosman M, de los Santos C, Fiala R, Hingerty BE, Ibanez V, Luna E, Harvey R, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1993 Apr 27;32(16):4145-55. doi: 10.1021/bi00067a001. Biochemistry. 1993. PMID: 8476845

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