Overton H - Search Results

1

Identification of a novel class of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents with protein tyrosine phosphatase inhibitory activity.

Guertin KR, Setti L, Qi L, Dunsdon RM, Dymock BW, Jones PS, Overton H, Taylor M, Williams G, Sergi JA, Wang K, Peng Y, Renzetti M, Boyce R, Falcioni F, Garippa R, Olivier AR. Guertin KR, et al. Among authors: overton h. Bioorg Med Chem Lett. 2003 Sep 1;13(17):2895-8. doi: 10.1016/s0960-894x(03)00623-1. Bioorg Med Chem Lett. 2003. PMID: 14611852

2

The design and synthesis of potent inhibitors of hepatitis C virus NS3-4A proteinase.

Attwood MR, Bennett JM, Campbell AD, Canning GG, Carr MG, Conway E, Dunsdon RM, Greening JR, Jones PS, Kay PB, Handa BK, Hurst DN, Jennings NS, Jordan S, Keech E, O'Brien MA, Overton HA, King-Underwood J, Raynham TM, Stenson KP, Wilkinson CS, Wilkinson TC, Wilson FX. Attwood MR, et al. Among authors: overton ha. Antivir Chem Chemother. 1999 Sep;10(5):259-73. doi: 10.1177/095632029901000505. Antivir Chem Chemother. 1999. PMID: 10574181 Free article.

3

Recombinant baculovirus-expressed NS3 proteinase of hepatitis C virus shows activity in cell-based and in vitro assays.

Overton H, McMillan D, Gillespie F, Mills J. Overton H, et al. J Gen Virol. 1995 Dec;76 ( Pt 12):3009-19. doi: 10.1099/0022-1317-76-12-3009. J Gen Virol. 1995. PMID: 8847506

4

Two-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitors.

Klumpp K, Hang JQ, Rajendran S, Yang Y, Derosier A, Wong Kai In P, Overton H, Parkes KE, Cammack N, Martin JA. Klumpp K, et al. Among authors: overton h. Nucleic Acids Res. 2003 Dec 1;31(23):6852-9. doi: 10.1093/nar/gkg881. Nucleic Acids Res. 2003. PMID: 14627818 Free PMC article.

5

Herpes simplex virus type 1 gene UL13 encodes a phosphoprotein that is a component of the virion.

Overton HA, McMillan DJ, Klavinskis LS, Hope L, Ritchie AJ, Wong-kai-in P. Overton HA, et al. Virology. 1992 Sep;190(1):184-92. doi: 10.1016/0042-6822(92)91204-8. Virology. 1992. PMID: 1326802

6

Activity of the isolated HIV RNase H domain and specific inhibition by N-hydroxyimides.

Hang JQ, Rajendran S, Yang Y, Li Y, In PW, Overton H, Parkes KE, Cammack N, Martin JA, Klumpp K. Hang JQ, et al. Among authors: overton h. Biochem Biophys Res Commun. 2004 Apr 30;317(2):321-9. doi: 10.1016/j.bbrc.2004.03.061. Biochem Biophys Res Commun. 2004. PMID: 15063760

7

Effect of two novel inhibitors of the human immunodeficiency virus protease on the maturation of the HIV gag and gag-pol polyproteins.

Overton HA, McMillan DJ, Gridley SJ, Brenner J, Redshaw S, Mills JS. Overton HA, et al. Virology. 1990 Nov;179(1):508-11. doi: 10.1016/0042-6822(90)90326-m. Virology. 1990. PMID: 2219737

8

Selective stimulation of hepatitis C virus and pestivirus NS5B RNA polymerase activity by GTP.

Lohmann V, Overton H, Bartenschlager R. Lohmann V, et al. Among authors: overton h. J Biol Chem. 1999 Apr 16;274(16):10807-15. doi: 10.1074/jbc.274.16.10807. J Biol Chem. 1999. PMID: 10196156 Free article.

9

The protease and gag gene products of the human immunodeficiency virus: authentic cleavage and post-translational modification in an insect cell expression system.

Overton HA, Fujii Y, Price IR, Jones IM. Overton HA, et al. Virology. 1989 May;170(1):107-16. doi: 10.1016/0042-6822(89)90357-7. Virology. 1989. PMID: 2655272

10

Production of host shutoff-defective mutants of herpes simplex virus type 1 by inactivation of the UL13 gene.

Overton H, McMillan D, Hope L, Wong-Kai-In P. Overton H, et al. Virology. 1994 Jul;202(1):97-106. doi: 10.1006/viro.1994.1326. Virology. 1994. PMID: 8009869

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