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Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway.
Basile JR, Afkhami T, Gutkind JS. Basile JR, et al. Mol Cell Biol. 2005 Aug;25(16):6889-98. doi: 10.1128/MCB.25.16.6889-6898.2005. Mol Cell Biol. 2005. PMID: 16055703 Free PMC article.
Interestingly, we have recently shown that Plexin-B1 is highly expressed in endothelial cells and that its activation by Semaphorin 4D elicits a potent proangiogenic response (J. R. Basile, A. Barac, T. Zhu, K. L. Guan, and J. S. Gutkind, Cancer Res. 64:5212- …
Interestingly, we have recently shown that Plexin-B1 is highly expressed in endothelial cells and that its activation by Semaphorin 4D elici …
440 results