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Beta-C-mannosides as selectin inhibitors.
Kaila N, Chen L, Thomas BE 4th, Tsao D, Tam S, Bedard PW, Camphausen RT, Alvarez JC, Ullas G. Kaila N, et al. Among authors: alvarez jc. J Med Chem. 2002 Apr 11;45(8):1563-6. doi: 10.1021/jm010390f. J Med Chem. 2002. PMID: 11931610
Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin.
Kaila N, Somers WS, Thomas BE, Thakker P, Janz K, DeBernardo S, Tam S, Moore WJ, Yang R, Wrona W, Bedard PW, Crommie D, Keith JC Jr, Tsao DH, Alvarez JC, Ni H, Marchese E, Patton JT, Magnani JL, Camphausen RT. Kaila N, et al. Among authors: alvarez jc. J Med Chem. 2005 Jun 30;48(13):4346-57. doi: 10.1021/jm050049l. J Med Chem. 2005. PMID: 15974587
Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors.
VanAlstine MA, Wentland MP, Alvarez J, Cao Q, Cohen DJ, Knapp BI, Bidlack JM. VanAlstine MA, et al. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2128-33. doi: 10.1016/j.bmcl.2013.01.117. Epub 2013 Feb 8. Bioorg Med Chem Lett. 2013. PMID: 23434225 Free PMC article.
Structure-based design of estrogen receptor-beta selective ligands.
Manas ES, Unwalla RJ, Xu ZB, Malamas MS, Miller CP, Harris HA, Hsiao C, Akopian T, Hum WT, Malakian K, Wolfrom S, Bapat A, Bhat RA, Stahl ML, Somers WS, Alvarez JC. Manas ES, et al. Among authors: alvarez jc. J Am Chem Soc. 2004 Nov 24;126(46):15106-19. doi: 10.1021/ja047633o. J Am Chem Soc. 2004. PMID: 15548008
389 results