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Design, synthesis, and biological activity of novel, potent, and selective (benzoylaminomethyl)thiophene sulfonamide inhibitors of c-Jun-N-terminal kinase.
Rückle T, Biamonte M, Grippi-Vallotton T, Arkinstall S, Cambet Y, Camps M, Chabert C, Church DJ, Halazy S, Jiang X, Martinou I, Nichols A, Sauer W, Gotteland JP. Rückle T, et al. Among authors: nichols a. J Med Chem. 2004 Dec 30;47(27):6921-34. doi: 10.1021/jm031112e. J Med Chem. 2004. PMID: 15615541
Discovery of a novel series of potent S1P1 agonists.
Crosignani S, Bombrun A, Covini D, Maio M, Marin D, Quattropani A, Swinnen D, Simpson D, Sauer W, Françon B, Martin T, Cambet Y, Nichols A, Martinou I, Burgat-Charvillon F, Rivron D, Donini C, Schott O, Eligert V, Novo-Perez L, Vitte PA, Arrighi JF. Crosignani S, et al. Among authors: nichols a. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1516-9. doi: 10.1016/j.bmcl.2010.01.102. Epub 2010 Jan 25. Bioorg Med Chem Lett. 2010. PMID: 20149651
MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha.
Castelli M, Camps M, Gillieron C, Leroy D, Arkinstall S, Rommel C, Nichols A. Castelli M, et al. Among authors: nichols a. J Biol Chem. 2004 Oct 22;279(43):44731-9. doi: 10.1074/jbc.M407669200. Epub 2004 Jul 28. J Biol Chem. 2004. PMID: 15284227 Free article.
Mitogen-activated protein (MAP) kinases play a central role in controlling a wide range of cellular functions following their activation by a variety of extracellular stimuli. ...Although ERK2 activity is regulated by its phosphorylation state, MKP3 is regula …
Mitogen-activated protein (MAP) kinases play a central role in controlling a wide range of cellular functions following their …
1,087 results