Mitch CH - Search Results

1

Na+-dependent high affinity binding of [3H]LY515300, a 3,4-dimethyl-4-(3-hydroxyphenyl)piperidine opioid receptor inverse agonist.

Statnick MA, Suter TM, Gackenheimer SL, Emmerson PJ, Quimby SJ, Gehlert DR, Wheeler WJ, Mitch CH. Statnick MA, et al. Among authors: mitch ch. Eur J Pharmacol. 2003 Dec 15;482(1-3):139-50. doi: 10.1016/j.ejphar.2003.09.043. Eur J Pharmacol. 2003. PMID: 14660015

2

Peptides that regulate food intake: antagonism of opioid receptors reduces body fat in obese rats by decreasing food intake and stimulating lipid utilization.

Statnick MA, Tinsley FC, Eastwood BJ, Suter TM, Mitch CH, Heiman ML. Statnick MA, et al. Among authors: mitch ch. Am J Physiol Regul Integr Comp Physiol. 2003 Jun;284(6):R1399-408. doi: 10.1152/ajpregu.00632.2002. Am J Physiol Regul Integr Comp Physiol. 2003. PMID: 12736177 Free article.

3

Na+ modulation, inverse agonism, and anorectic potency of 4-phenylpiperidine opioid antagonists.

Emmerson PJ, McKinzie JH, Surface PL, Suter TM, Mitch CH, Statnick MA. Emmerson PJ, et al. Among authors: mitch ch. Eur J Pharmacol. 2004 Jun 28;494(2-3):121-30. doi: 10.1016/j.ejphar.2004.04.050. Eur J Pharmacol. 2004. PMID: 15212965

4

Localization of opioid receptor antagonist [3H]-LY255582 binding sites in mouse brain: comparison with the distribution of mu, delta and kappa binding sites.

Gackenheimer SL, Suter TM, Pintar JE, Quimby SJ, Wheeler WJ, Mitch CH, Gehlert DR, Statnick MA. Gackenheimer SL, et al. Among authors: mitch ch. Neuropeptides. 2005 Dec;39(6):559-67. doi: 10.1016/j.npep.2005.09.006. Epub 2005 Nov 9. Neuropeptides. 2005. PMID: 16289278

5

Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1.

Takeuchi K, Holloway WG, McKinzie JH, Suter TM, Statnick MA, Surface PL, Emmerson PJ, Thomas EM, Siegel MG, Matt JE, Wolfe CN, Mitch CH. Takeuchi K, et al. Among authors: mitch ch. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5349-52. doi: 10.1016/j.bmcl.2007.08.008. Epub 2007 Aug 11. Bioorg Med Chem Lett. 2007. PMID: 17720493

6

In vivo rat brain opioid receptor binding of LY255582 assessed with a novel method using LC/MS/MS and the administration of three tracers simultaneously.

Need AB, McKinzie JH, Mitch CH, Statnick MA, Phebus LA. Need AB, et al. Among authors: mitch ch. Life Sci. 2007 Oct 13;81(17-18):1389-96. doi: 10.1016/j.lfs.2007.09.005. Epub 2007 Sep 19. Life Sci. 2007. PMID: 17935738

7

Effects of kappa opioid receptor agonists on attention as assessed by a 5-choice serial reaction time task in rats.

Shannon HE, Eberle EL, Mitch CH, McKinzie DL, Statnick MA. Shannon HE, et al. Among authors: mitch ch. Neuropharmacology. 2007 Dec;53(8):930-41. doi: 10.1016/j.neuropharm.2007.09.002. Epub 2007 Sep 20. Neuropharmacology. 2007. PMID: 17959202

8

Structure activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 2.

Takeuchi K, Holloway WG, Mitch CH, Quimby SJ, McKinzie JH, Suter TM, Statnick MA, Surface PL, Emmerson PJ, Thomas EM, Siegel MG. Takeuchi K, et al. Among authors: mitch ch. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6841-6. doi: 10.1016/j.bmcl.2007.10.025. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17980586

9

Activation of mesolimbic dopamine neurons during novel and daily limited access to palatable food is blocked by the opioid antagonist LY255582.

Sahr AE, Sindelar DK, Alexander-Chacko JT, Eastwood BJ, Mitch CH, Statnick MA. Sahr AE, et al. Among authors: mitch ch. Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R463-71. doi: 10.1152/ajpregu.00390.2007. Epub 2008 Jun 4. Am J Physiol Regul Integr Comp Physiol. 2008. PMID: 18525013 Free article.

10

Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer.

Mitch CH, Quimby SJ, Diaz N, Pedregal C, de la Torre MG, Jimenez A, Shi Q, Canada EJ, Kahl SD, Statnick MA, McKinzie DL, Benesh DR, Rash KS, Barth VN. Mitch CH, et al. J Med Chem. 2011 Dec 8;54(23):8000-12. doi: 10.1021/jm200789r. Epub 2011 Oct 26. J Med Chem. 2011. PMID: 21958337

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