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Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity.
Stratmann T, Martin-Orozco N, Mallet-Designe V, Poirot L, McGavern D, Losyev G, Dobbs CM, Oldstone MB, Yoshida K, Kikutani H, Mathis D, Benoist C, Haskins K, Teyton L. Stratmann T, et al. Among authors: poirot l. J Clin Invest. 2003 Sep;112(6):902-14. doi: 10.1172/JCI18337. J Clin Invest. 2003. PMID: 12975475 Free PMC article.
Gene expression microarrays: glimpses of the immunological genome.
Hyatt G, Melamed R, Park R, Seguritan R, Laplace C, Poirot L, Zucchelli S, Obst R, Matos M, Venanzi E, Goldrath A, Nguyen L, Luckey J, Yamagata T, Herman A, Jacobs J, Mathis D, Benoist C. Hyatt G, et al. Among authors: poirot l. Nat Immunol. 2006 Jul;7(7):686-91. doi: 10.1038/ni0706-686. Nat Immunol. 2006. PMID: 16785882
The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain.
Beisner DR, Langerak P, Parker AE, Dahlberg C, Otero FJ, Sutton SE, Poirot L, Barnes W, Young MA, Niessen S, Wiltshire T, Bodendorf U, Martoglio B, Cravatt B, Cooke MP. Beisner DR, et al. Among authors: poirot l. J Exp Med. 2013 Jan 14;210(1):23-30. doi: 10.1084/jem.20121072. Epub 2012 Dec 24. J Exp Med. 2013. PMID: 23267013 Free PMC article.
'Off-the-shelf' allogeneic CAR T cells: development and challenges.
Depil S, Duchateau P, Grupp SA, Mufti G, Poirot L. Depil S, et al. Among authors: poirot l. Nat Rev Drug Discov. 2020 Mar;19(3):185-199. doi: 10.1038/s41573-019-0051-2. Epub 2020 Jan 3. Nat Rev Drug Discov. 2020. PMID: 31900462 Review.
Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing.
Jo S, Das S, Williams A, Chretien AS, Pagliardini T, Le Roy A, Fernandez JP, Le Clerre D, Jahangiri B, Chion-Sotinel I, Rozlan S, Dessez E, Gouble A, Dusséaux M, Galetto R, Duclert A, Marcenaro E, Devillier R, Olive D, Duchateau P, Poirot L, Valton J. Jo S, et al. Among authors: poirot l. Nat Commun. 2022 Jun 30;13(1):3453. doi: 10.1038/s41467-022-30896-2. Nat Commun. 2022. PMID: 35773273 Free PMC article.
38 results