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Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478.
Johns TG, Luwor RB, Murone C, Walker F, Weinstock J, Vitali AA, Perera RM, Jungbluth AA, Stockert E, Old LJ, Nice EC, Burgess AW, Scott AM. Johns TG, et al. Among authors: perera rm. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15871-6. doi: 10.1073/pnas.2036503100. Epub 2003 Dec 15. Proc Natl Acad Sci U S A. 2003. PMID: 14676326 Free PMC article.
Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity.
Perera RM, Narita Y, Furnari FB, Gan HK, Murone C, Ahlkvist M, Luwor RB, Burgess AW, Stockert E, Jungbluth AA, Old LJ, Cavenee WK, Scott AM, Johns TG. Perera RM, et al. Clin Cancer Res. 2005 Sep 1;11(17):6390-9. doi: 10.1158/1078-0432.CCR-04-2653. Clin Cancer Res. 2005. PMID: 16144944
Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
Lee JJ, Perera RM, Wang H, Wu DC, Liu XS, Han S, Fitamant J, Jones PD, Ghanta KS, Kawano S, Nagle JM, Deshpande V, Boucher Y, Kato T, Chen JK, Willmann JK, Bardeesy N, Beachy PA. Lee JJ, et al. Among authors: perera rm. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3091-100. doi: 10.1073/pnas.1411679111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024225 Free PMC article.
The Lysosome as a Regulatory Hub.
Perera RM, Zoncu R. Perera RM, et al. Annu Rev Cell Dev Biol. 2016 Oct 6;32:223-253. doi: 10.1146/annurev-cellbio-111315-125125. Epub 2016 Aug 3. Annu Rev Cell Dev Biol. 2016. PMID: 27501449 Free PMC article. Review.
54 results