Jones BC - Search Results

1

Reaction phenotyping in drug discovery: moving forward with confidence?

Williams JA, Hurst SI, Bauman J, Jones BC, Hyland R, Gibbs JP, Obach RS, Ball SE. Williams JA, et al. Among authors: jones bc. Curr Drug Metab. 2003 Dec;4(6):527-34. doi: 10.2174/1389200033489235. Curr Drug Metab. 2003. PMID: 14683480 Review.

2

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios.

Williams JA, Hyland R, Jones BC, Smith DA, Hurst S, Goosen TC, Peterkin V, Koup JR, Ball SE. Williams JA, et al. Among authors: jones bc. Drug Metab Dispos. 2004 Nov;32(11):1201-8. doi: 10.1124/dmd.104.000794. Epub 2004 Aug 10. Drug Metab Dispos. 2004. PMID: 15304429 Review.

3

Utility of human/human-derived reagents in drug discovery and development: An industrial perspective.

Hyland R, Jones B, van de Waterbeemd H. Hyland R, et al. Environ Toxicol Pharmacol. 2006 Feb;21(2):179-83. doi: 10.1016/j.etap.2005.07.007. Epub 2005 Aug 10. Environ Toxicol Pharmacol. 2006. PMID: 21783655

4

Induction of cytochrome P450: assessment in an immortalized human hepatocyte cell line (Fa2N4) using a novel higher throughput cocktail assay.

Youdim KA, Tyman CA, Jones BC, Hyland R. Youdim KA, et al. Among authors: jones bc. Drug Metab Dispos. 2007 Feb;35(2):275-82. doi: 10.1124/dmd.106.012864. Epub 2006 Nov 15. Drug Metab Dispos. 2007. PMID: 17108058

5

Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole.

Hyland R, Jones BC, Smith DA. Hyland R, et al. Among authors: jones bc. Drug Metab Dispos. 2003 May;31(5):540-7. doi: 10.1124/dmd.31.5.540. Drug Metab Dispos. 2003. PMID: 12695341

6

Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.

Hyland R, Roe EG, Jones BC, Smith DA. Hyland R, et al. Among authors: jones bc. Br J Clin Pharmacol. 2001 Mar;51(3):239-48. doi: 10.1046/j.1365-2125.2001.00318.x. Br J Clin Pharmacol. 2001. PMID: 11298070 Free PMC article.

7

Maraviroc: in vitro assessment of drug-drug interaction potential.

Hyland R, Dickins M, Collins C, Jones H, Jones B. Hyland R, et al. Br J Clin Pharmacol. 2008 Oct;66(4):498-507. doi: 10.1111/j.1365-2125.2008.03198.x. Epub 2008 Apr 10. Br J Clin Pharmacol. 2008. PMID: 18647303 Free PMC article.

8

Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo data.

Walker DK, Alabaster CT, Congrave GS, Hargreaves MB, Hyland R, Jones BC, Reed LJ, Smith DA. Walker DK, et al. Among authors: jones bc. Drug Metab Dispos. 1996 Apr;24(4):447-55. Drug Metab Dispos. 1996. PMID: 8801060

9

Investigation into UDP-glucuronosyltransferase (UGT) enzyme kinetics of imidazole- and triazole-containing antifungal drugs in human liver microsomes and recombinant UGT enzymes.

Bourcier K, Hyland R, Kempshall S, Jones R, Maximilien J, Irvine N, Jones B. Bourcier K, et al. Drug Metab Dispos. 2010 Jun;38(6):923-9. doi: 10.1124/dmd.109.030676. Epub 2010 Mar 19. Drug Metab Dispos. 2010. PMID: 20304965

10

Interaction of terfenadine and its primary metabolites with cytochrome P450 2D6.

Jones BC, Hyland R, Ackland M, Tyman CA, Smith DA. Jones BC, et al. Drug Metab Dispos. 1998 Sep;26(9):875-82. Drug Metab Dispos. 1998. PMID: 9733666

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

484 results

Search Page

Filters