Wandless TJ - Search Results

1

Conditional protein alleles using knockin mice and a chemical inducer of dimerization.

Stankunas K, Bayle JH, Gestwicki JE, Lin YM, Wandless TJ, Crabtree GR. Stankunas K, et al. Among authors: wandless tj. Mol Cell. 2003 Dec;12(6):1615-24. doi: 10.1016/s1097-2765(03)00491-x. Mol Cell. 2003. PMID: 14690613 Free article.

2

Controlling signal transduction with synthetic ligands.

Spencer DM, Wandless TJ, Schreiber SL, Crabtree GR. Spencer DM, et al. Among authors: wandless tj. Science. 1993 Nov 12;262(5136):1019-24. doi: 10.1126/science.7694365. Science. 1993. PMID: 7694365

3

Affinity modulation of small-molecule ligands by borrowing endogenous protein surfaces.

Briesewitz R, Ray GT, Wandless TJ, Crabtree GR. Briesewitz R, et al. Among authors: wandless tj. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):1953-8. doi: 10.1073/pnas.96.5.1953. Proc Natl Acad Sci U S A. 1999. PMID: 10051576 Free PMC article.

4

Calcineurin inhibitors and the generalization of the presenting protein strategy.

Vogel KW, Briesewitz R, Wandless TJ, Crabtree GR. Vogel KW, et al. Among authors: wandless tj. Adv Protein Chem. 2001;56:253-91. doi: 10.1016/s0065-3233(01)56008-8. Adv Protein Chem. 2001. PMID: 11329856 Review. No abstract available.

5

A bifunctional molecule that displays context-dependent cellular activity.

Braun PD, Barglow KT, Lin YM, Akompong T, Briesewitz R, Ray GT, Haldar K, Wandless TJ. Braun PD, et al. Among authors: wandless tj. J Am Chem Soc. 2003 Jun 25;125(25):7575-80. doi: 10.1021/ja035176q. J Am Chem Soc. 2003. PMID: 12812497

6

Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity.

Bayle JH, Grimley JS, Stankunas K, Gestwicki JE, Wandless TJ, Crabtree GR. Bayle JH, et al. Among authors: wandless tj. Chem Biol. 2006 Jan;13(1):99-107. doi: 10.1016/j.chembiol.2005.10.017. Chem Biol. 2006. PMID: 16426976

7

A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules.

Banaszynski LA, Chen LC, Maynard-Smith LA, Ooi AG, Wandless TJ. Banaszynski LA, et al. Among authors: wandless tj. Cell. 2006 Sep 8;126(5):995-1004. doi: 10.1016/j.cell.2006.07.025. Cell. 2006. PMID: 16959577 Free PMC article.

8

Engineering small molecule specificity in nearly identical cellular environments.

Sellmyer MA, Stankunas K, Briesewitz R, Crabtree GR, Wandless TJ. Sellmyer MA, et al. Among authors: wandless tj. Bioorg Med Chem Lett. 2007 May 15;17(10):2703-5. doi: 10.1016/j.bmcl.2007.03.012. Epub 2007 Mar 12. Bioorg Med Chem Lett. 2007. PMID: 17383876 Free PMC article.

9

Rescue of degradation-prone mutants of the FK506-rapamycin binding (FRB) protein with chemical ligands.

Stankunas K, Bayle JH, Havranek JJ, Wandless TJ, Baker D, Crabtree GR, Gestwicki JE. Stankunas K, et al. Among authors: wandless tj. Chembiochem. 2007 Jul 9;8(10):1162-9. doi: 10.1002/cbic.200700087. Chembiochem. 2007. PMID: 17525916 Free article.

10

A general chemical method to regulate protein stability in the mammalian central nervous system.

Iwamoto M, Björklund T, Lundberg C, Kirik D, Wandless TJ. Iwamoto M, et al. Among authors: wandless tj. Chem Biol. 2010 Sep 24;17(9):981-8. doi: 10.1016/j.chembiol.2010.07.009. Chem Biol. 2010. PMID: 20851347 Free PMC article.

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