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Page 1
Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity.
Pajvani UB, Hawkins M, Combs TP, Rajala MW, Doebber T, Berger JP, Wagner JA, Wu M, Knopps A, Xiang AH, Utzschneider KM, Kahn SE, Olefsky JM, Buchanan TA, Scherer PE. Pajvani UB, et al. Among authors: doebber t. J Biol Chem. 2004 Mar 26;279(13):12152-62. doi: 10.1074/jbc.M311113200. Epub 2003 Dec 29. J Biol Chem. 2004. PMID: 14699128 Free article.
Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization.
Combs TP, Wagner JA, Berger J, Doebber T, Wang WJ, Zhang BB, Tanen M, Berg AH, O'Rahilly S, Savage DB, Chatterjee K, Weiss S, Larson PJ, Gottesdiener KM, Gertz BJ, Charron MJ, Scherer PE, Moller DE. Combs TP, et al. Among authors: doebber t. Endocrinology. 2002 Mar;143(3):998-1007. doi: 10.1210/endo.143.3.8662. Endocrinology. 2002. PMID: 11861525 Clinical Trial.
Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice.
Zhang B, Graziano MP, Doebber TW, Leibowitz MD, White-Carrington S, Szalkowski DM, Hey PJ, Wu M, Cullinan CA, Bailey P, Lollmann B, Frederich R, Flier JS, Strader CD, Smith RG. Zhang B, et al. Among authors: doebber tw. J Biol Chem. 1996 Apr 19;271(16):9455-9. doi: 10.1074/jbc.271.16.9455. J Biol Chem. 1996. PMID: 8621615 Free article.
Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects.
Berger J, Leibowitz MD, Doebber TW, Elbrecht A, Zhang B, Zhou G, Biswas C, Cullinan CA, Hayes NS, Li Y, Tanen M, Ventre J, Wu MS, Berger GD, Mosley R, Marquis R, Santini C, Sahoo SP, Tolman RL, Smith RG, Moller DE. Berger J, et al. Among authors: doebber tw. J Biol Chem. 1999 Mar 5;274(10):6718-25. doi: 10.1074/jbc.274.10.6718. J Biol Chem. 1999. PMID: 10037770 Free article.
A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.
Chang CH, McNamara LA, Wu MS, Muise ES, Tan Y, Wood HB, Meinke PT, Thompson JR, Doebber TW, Berger JP, McCann ME. Chang CH, et al. Among authors: doebber tw. Eur J Pharmacol. 2008 Apr 14;584(1):192-201. doi: 10.1016/j.ejphar.2007.12.036. Epub 2008 Feb 14. Eur J Pharmacol. 2008. PMID: 18346728
Phenylacetic acid derivatives as hPPAR agonists.
Santini C, Berger GD, Han W, Mosley R, MacNaul K, Berger J, Doebber T, Wu M, Moller DE, Tolman RL, Sahoo SP. Santini C, et al. Among authors: doebber t. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1277-80. doi: 10.1016/s0960-894x(03)00115-x. Bioorg Med Chem Lett. 2003. PMID: 12657263
Individual and combined effects of peroxisome proliferator-activated receptor and {gamma} agonists, fenofibrate and rosiglitazone, on biomarkers of lipid and glucose metabolism in healthy nondiabetic volunteers.
Wagner JA, Larson PJ, Weiss S, Miller JL, Doebber TW, Wu MS, Moller DE, Gottesdiener KM. Wagner JA, et al. Among authors: doebber tw. J Clin Pharmacol. 2005 May;45(5):504-13. doi: 10.1177/0091270004273136. J Clin Pharmacol. 2005. PMID: 15831773 Clinical Trial.
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