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SSR126768A (4-chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, hydrochloride): a new selective and orally active oxytocin receptor antagonist for the prevention of preterm labor.
Serradeil-Le Gal C, Valette G, Foulon L, Germain G, Advenier C, Naline E, Bardou M, Martinolle JP, Pouzet B, Raufaste D, Garcia C, Double-Cazanave E, Pauly M, Pascal M, Barbier A, Scatton B, Maffrand JP, Le Fur G. Serradeil-Le Gal C, et al. Among authors: germain g. J Pharmacol Exp Ther. 2004 Apr;309(1):414-24. doi: 10.1124/jpet.103.061200. Epub 2004 Jan 13. J Pharmacol Exp Ther. 2004. PMID: 14722330
In vitro and in vivo pharmacological characterization of ethyl-4-[trans-4-[((2S)-2-hydroxy-3-[4-hydroxy-3[(methylsulfonyl)amino]-phenoxy]propyl) amino]cyclohexyl]benzoate hydrochloride (SAR150640), a new potent and selective human beta3-adrenoceptor agonist for the treatment of preterm labor.
Croci T, Cecchi R, Marini P, Rouget C, Viviani N, Germain G, Guagnini F, Fradin Y, Descamps L, Pascal M, Advenier C, Breuiller-Fouché M, Leroy MJ, Bardou M. Croci T, et al. Among authors: germain g. J Pharmacol Exp Ther. 2007 Jun;321(3):1118-26. doi: 10.1124/jpet.106.119123. Epub 2007 Mar 9. J Pharmacol Exp Ther. 2007. PMID: 17351104
What is the future of tocolysis?
Terrien J, Marque C, Germain G. Terrien J, et al. Among authors: germain g. Eur J Obstet Gynecol Reprod Biol. 2004 Nov 15;117 Suppl 1:S10-4. doi: 10.1016/j.ejogrb.2004.07.009. Eur J Obstet Gynecol Reprod Biol. 2004. PMID: 15530707 Review.
209 results