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A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis.
Khor CC, Chapman SJ, Vannberg FO, Dunne A, Murphy C, Ling EY, Frodsham AJ, Walley AJ, Kyrieleis O, Khan A, Aucan C, Segal S, Moore CE, Knox K, Campbell SJ, Lienhardt C, Scott A, Aaby P, Sow OY, Grignani RT, Sillah J, Sirugo G, Peshu N, Williams TN, Maitland K, Davies RJ, Kwiatkowski DP, Day NP, Yala D, Crook DW, Marsh K, Berkley JA, O'Neill LA, Hill AV. Khor CC, et al. Among authors: aucan c. Nat Genet. 2007 Apr;39(4):523-8. doi: 10.1038/ng1976. Epub 2007 Feb 25. Nat Genet. 2007. PMID: 17322885 Free PMC article.
Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus.
Khor CC, Vannberg FO, Chapman SJ, Walley A, Aucan C, Loke H, White NJ, Peto T, Khor LK, Kwiatkowski D, Day N, Scott A, Berkley JA, Marsh K, Peshu N, Maitland K, Williams TN, Hill AV. Khor CC, et al. Among authors: aucan c. Genes Immun. 2007 Oct;8(7):570-6. doi: 10.1038/sj.gene.6364417. Epub 2007 Aug 16. Genes Immun. 2007. PMID: 17703179 Free PMC article.
18 results