Sousa EH - Search Results

1

An inorganic iron complex that inhibits wild-type and an isoniazid-resistant mutant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis.

Oliveira JS, Sousa EH, Basso LA, Palaci M, Dietze R, Santos DS, Moreira IS. Oliveira JS, et al. Among authors: sousa eh. Chem Commun (Camb). 2004 Feb 7;(3):312-3. doi: 10.1039/b313592f. Epub 2004 Jan 7. Chem Commun (Camb). 2004. PMID: 14740053

2

Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate(III)/(II) complexes: a model system for the in vitro activation of thioamides anti-tuberculosis drugs.

Sousa EH, Pontes DL, Diógenes IC, Lopes LG, Oliveira JS, Basso LA, Santos DS, Moreira IS. Sousa EH, et al. J Inorg Biochem. 2005 Feb;99(2):368-75. doi: 10.1016/j.jinorgbio.2004.10.004. J Inorg Biochem. 2005. PMID: 15621268

3

Is IQG-607 a Potential Metallodrug or Metallopro-Drug With a Defined Molecular Target in Mycobacterium tuberculosis?

Abbadi BL, Rodrigues-Junior VDS, Dadda ADS, Pissinate K, Villela AD, Campos MM, Lopes LGF, Bizarro CV, Machado P, Sousa EHS, Basso LA. Abbadi BL, et al. Front Microbiol. 2018 May 1;9:880. doi: 10.3389/fmicb.2018.00880. eCollection 2018. Front Microbiol. 2018. PMID: 29765372 Free PMC article. Review.

4

A bioinorganic chemistry perspective on the roles of metals as drugs and targets against Mycobacterium tuberculosis - a journey of opportunities.

Lopes LGF , Carvalho EM , Sousa EHS . Lopes LGF , et al. Dalton Trans. 2020 Nov 25;49(45):15988-16003. doi: 10.1039/d0dt01365j. Dalton Trans. 2020. PMID: 32583835 Review.

5

Potential therapeutic approaches for a sleeping pathogen: tuberculosis a case for bioinorganic chemistry.

Sousa EHS, Diógenes ICN, Lopes LGF, Moura JJG. Sousa EHS, et al. J Biol Inorg Chem. 2020 Aug;25(5):685-704. doi: 10.1007/s00775-020-01803-1. Epub 2020 Jul 16. J Biol Inorg Chem. 2020. PMID: 32676771 Review.

6

Non-nitric oxide based metallovasodilators: synthesis, reactivity and biological studies.

Sá DS, Fernandes AF, Silva CD, Costa PP, Fonteles MC, Nascimento NR, Lopes LG, Sousa EH. Sá DS, et al. Among authors: sousa eh. Dalton Trans. 2015 Aug 14;44(30):13633-40. doi: 10.1039/c5dt01582k. Dalton Trans. 2015. PMID: 26143862

7

Mechanism and biological implications of the NO release of cis-[Ru(bpy)2L(NO)](n+) complexes: a key role of physiological thiols.

Silva FO, Cândido MC, Holanda AK, Diógenes IC, Sousa EH, Lopes LG. Silva FO, et al. Among authors: sousa eh. J Inorg Biochem. 2011 May;105(5):624-9. doi: 10.1016/j.jinorgbio.2011.02.004. Epub 2011 Feb 19. J Inorg Biochem. 2011. PMID: 21443852

8

A spectroelectrochemical investigation of the heme-based sensor DevS from Mycobacterium tuberculosis: a redox versus oxygen sensor.

Barreto GA, Carepo MSP, Gondim ACS, Guimarães WG, Lopes LGF, Bernhardt PV, Paulo TF, Sousa EHS, Diógenes ICN. Barreto GA, et al. FEBS J. 2019 Nov;286(21):4278-4293. doi: 10.1111/febs.14974. Epub 2019 Jul 11. FEBS J. 2019. PMID: 31254441 Free article.

9

The Heme-Based Oxygen Sensor Rhizobium etli FixL: Influence of Auxiliary Ligands on Heme Redox Potential and Implications on the Enzyme Activity.

Honorio-Felício N, Carepo MS, de F Paulo T, de França Lopes LG, Sousa EH, Diógenes IC, Bernhardt PV. Honorio-Felício N, et al. Among authors: sousa eh. J Inorg Biochem. 2016 Nov;164:34-41. doi: 10.1016/j.jinorgbio.2016.08.009. Epub 2016 Aug 26. J Inorg Biochem. 2016. PMID: 27614714

10

Insights into signal transduction by a hybrid FixL: Denaturation study of on and off states of a multi-domain oxygen sensor.

Guimarães WG, Gondim ACS, Costa PMDS, Gilles-Gonzalez MA, Lopes LGF, Carepo MSP, Sousa EHS. Guimarães WG, et al. J Inorg Biochem. 2017 Jul;172:129-137. doi: 10.1016/j.jinorgbio.2017.04.013. Epub 2017 Apr 13. J Inorg Biochem. 2017. PMID: 28458146

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