Kulagowski JJ - Search Results

1

Thiazoles and thiopyridines: novel series of high affinity h5HT(7) ligands.

Thomson CG, Beer MS, Curtis NR, Diggle HJ, Handford E, Kulagowski JJ. Thomson CG, et al. Among authors: kulagowski jj. Bioorg Med Chem Lett. 2004 Feb 9;14(3):677-80. doi: 10.1016/j.bmcl.2003.11.050. Bioorg Med Chem Lett. 2004. PMID: 14741267

2

Novel N1-(benzyl)cinnamamidine derived NR2B subtype-selective NMDA receptor antagonists.

Curtis NR, Diggle HJ, Kulagowski JJ, London C, Grimwood S, Hutson PH, Murray F, Richards P, Macaulay A, Wafford KA. Curtis NR, et al. Among authors: kulagowski jj. Bioorg Med Chem Lett. 2003 Feb 24;13(4):693-6. doi: 10.1016/s0960-894x(02)01060-0. Bioorg Med Chem Lett. 2003. PMID: 12639560

3

Orally efficacious NR2B-selective NMDA receptor antagonists.

Claiborne CF, McCauley JA, Libby BE, Curtis NR, Diggle HJ, Kulagowski JJ, Michelson SR, Anderson KD, Claremon DA, Freidinger RM, Bednar RA, Mosser SD, Gaul SL, Connolly TM, Condra CL, Bednar B, Stump GL, Lynch JJ, Macaulay A, Wafford KA, Koblan KS, Liverton NJ. Claiborne CF, et al. Among authors: kulagowski jj. Bioorg Med Chem Lett. 2003 Feb 24;13(4):697-700. doi: 10.1016/s0960-894x(02)01061-2. Bioorg Med Chem Lett. 2003. PMID: 12639561

4

Synthesis and structure-activity relationships of 8-azabicyclo[3.2.1]octane benzylamine NK1 antagonists.

Thomson CG, Carlson E, Chicchi GG, Kulagowski JJ, Kurtz MM, Swain CJ, Tsao KL, Wheeldon A. Thomson CG, et al. Among authors: kulagowski jj. Bioorg Med Chem Lett. 2006 Feb 15;16(4):811-4. doi: 10.1016/j.bmcl.2005.11.026. Epub 2005 Nov 22. Bioorg Med Chem Lett. 2006. PMID: 16307878

5

Aminoalkyl phenyl sulfones--a novel series of 5-HT7 receptor ligands.

Raubo P, Beer MS, Hunt PA, Huscroft IT, London C, Stanton JA, Kulagowski JJ. Raubo P, et al. Among authors: kulagowski jj. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1255-8. doi: 10.1016/j.bmcl.2005.11.067. Epub 2005 Dec 7. Bioorg Med Chem Lett. 2006. PMID: 16337790

6

Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands.

Curtis NR, Kulagowski JJ, Leeson PD, Ridgill MP, Emms F, Freedman SB, Patel S, Patel S. Curtis NR, et al. Among authors: kulagowski jj. Bioorg Med Chem Lett. 1999 Feb 22;9(4):585-8. doi: 10.1016/s0960-894x(99)00025-6. Bioorg Med Chem Lett. 1999. PMID: 10098669

7

3'-(Arylmethyl)- and 3'-(aryloxy)-3-phenyl-4-hydroxyquinolin-2(1H)-ones: orally active antagonists of the glycine site on the NMDA receptor.

Kulagowski JJ, Baker R, Curtis NR, Leeson PD, Mawer IM, Moseley AM, Ridgill MP, Rowley M, Stansfield I, Foster AC, et al. Kulagowski JJ, et al. J Med Chem. 1994 May 13;37(10):1402-5. doi: 10.1021/jm00036a002. J Med Chem. 1994. PMID: 8182696 No abstract available.

8

3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.

Kulagowski JJ, Broughton HB, Curtis NR, Mawer IM, Ridgill MP, Baker R, Emms F, Freedman SB, Marwood R, Patel S, Patel S, Ragan CI, Leeson PD. Kulagowski JJ, et al. J Med Chem. 1996 May 10;39(10):1941-2. doi: 10.1021/jm9600712. J Med Chem. 1996. PMID: 8642550 No abstract available.

9

Stereocontrolled syntheses of epimeric 3-aryl-6-phenyl-1-oxa-7-azaspiro(4.5)decane NK-1 receptor antagonist precursors.

Kulagowski JJ, Curtis NR, Swain CJ, Williams BJ. Kulagowski JJ, et al. Org Lett. 2001 Mar 8;3(5):667-70. doi: 10.1021/ol006944a. Org Lett. 2001. PMID: 11259032

10

The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor.

Guscott MR, Egan E, Cook GP, Stanton JA, Beer MS, Rosahl TW, Hartmann S, Kulagowski J, McAllister G, Fone KC, Hutson PH. Guscott MR, et al. Neuropharmacology. 2003 Jun;44(8):1031-7. doi: 10.1016/s0028-3908(03)00117-5. Neuropharmacology. 2003. PMID: 12763096

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