Xiao L - Search Results

1

Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding.

Xiao L, Madison V, Chau AS, Loebenberg D, Palermo RE, McNicholas PM. Xiao L, et al. Antimicrob Agents Chemother. 2004 Feb;48(2):568-74. doi: 10.1128/AAC.48.2.568-574.2004. Antimicrob Agents Chemother. 2004. PMID: 14742211 Free PMC article.

2

Insights from a three-dimensional model into ligand binding to constitutive active receptor.

Xiao L, Cui X, Madison V, White RE, Cheng KC. Xiao L, et al. Drug Metab Dispos. 2002 Sep;30(9):951-6. doi: 10.1124/dmd.30.9.951. Drug Metab Dispos. 2002. PMID: 12167558

3

Crystal structure of the catalytic domain of human ADAM33.

Orth P, Reichert P, Wang W, Prosise WW, Yarosh-Tomaine T, Hammond G, Ingram RN, Xiao L, Mirza UA, Zou J, Strickland C, Taremi SS, Le HV, Madison V. Orth P, et al. Among authors: xiao l. J Mol Biol. 2004 Jan 2;335(1):129-37. doi: 10.1016/j.jmb.2003.10.037. J Mol Biol. 2004. PMID: 14659745

4

Improved activity and thermostability of Candida antarctica lipase B by DNA family shuffling.

Suen WC, Zhang N, Xiao L, Madison V, Zaks A. Suen WC, et al. Among authors: xiao l. Protein Eng Des Sel. 2004 Feb;17(2):133-40. doi: 10.1093/protein/gzh017. Epub 2004 Jan 12. Protein Eng Des Sel. 2004. PMID: 15047909

5

Improving tolerance of Candida antarctica lipase B towards irreversible thermal inactivation through directed evolution.

Zhang N, Suen WC, Windsor W, Xiao L, Madison V, Zaks A. Zhang N, et al. Among authors: xiao l. Protein Eng. 2003 Aug;16(8):599-605. doi: 10.1093/protein/gzg074. Protein Eng. 2003. PMID: 12968077

6

Sphingolipid biosynthesis in pathogenic fungi: identification and characterization of the 3-ketosphinganine reductase activity of Candida albicans and Aspergillus fumigatus.

Fornarotto M, Xiao L, Hou Y, Koch KA, Chang E, O'Malley RM, Black TA, Cable MB, Walker SS. Fornarotto M, et al. Among authors: xiao l. Biochim Biophys Acta. 2006 Jan;1761(1):52-63. doi: 10.1016/j.bbalip.2005.11.013. Epub 2006 Jan 6. Biochim Biophys Acta. 2006. PMID: 16431155

7

Broad coverage of genetically diverse strains of Clostridium difficile by actoxumab and bezlotoxumab predicted by in vitro neutralization and epitope modeling.

Hernandez LD, Racine F, Xiao L, DiNunzio E, Hairston N, Sheth PR, Murgolo NJ, Therien AG. Hernandez LD, et al. Among authors: xiao l. Antimicrob Agents Chemother. 2015 Feb;59(2):1052-60. doi: 10.1128/AAC.04433-14. Epub 2014 Dec 1. Antimicrob Agents Chemother. 2015. PMID: 25451052 Free PMC article. Clinical Trial.

8

Purification and characterization of truncated human AMPK alpha 2 beta 2 gamma 3 heterotrimer from baculovirus-infected insect cells.

Ramanathan L, Sheth PR, Ogas P, Xiao L, Le HV. Ramanathan L, et al. Among authors: xiao l. Protein Expr Purif. 2010 Mar;70(1):13-22. doi: 10.1016/j.pep.2009.10.007. Epub 2009 Oct 30. Protein Expr Purif. 2010. PMID: 19836452

9

Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography.

Orth P, Xiao L, Hernandez LD, Reichert P, Sheth PR, Beaumont M, Yang X, Murgolo N, Ermakov G, DiNunzio E, Racine F, Karczewski J, Secore S, Ingram RN, Mayhood T, Strickland C, Therien AG. Orth P, et al. Among authors: xiao l. J Biol Chem. 2014 Jun 27;289(26):18008-21. doi: 10.1074/jbc.M114.560748. Epub 2014 May 12. J Biol Chem. 2014. PMID: 24821719 Free PMC article.

10

Co-induction of CYP3A12 and 3A26 in dog liver slices by xenobiotics: species difference between human and dog CYP3A induction.

Chen J, Tran C, Xiao L, Palamanda J, Klapmuts T, Kumari P, Lin X, Wang EJ, Gu YZ, Humphries M, Uss AS, Cheng KC. Chen J, et al. Among authors: xiao l. Drug Metab Lett. 2009 Jan;3(1):61-6. doi: 10.2174/187231209787176399. Drug Metab Lett. 2009. PMID: 19356119

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