Espinosa A - Search Results

1

Distamycin A as stem of DNA minor groove alkylating agents.

Baraldi PG, Nûnez Mdel C, Espinosa A, Romagnoli R. Baraldi PG, et al. Among authors: espinosa a. Curr Top Med Chem. 2004;4(2):231-9. doi: 10.2174/1568026043451474. Curr Top Med Chem. 2004. PMID: 14754456 Review.

2

Design, synthesis, and biological activity of hybrid compounds between uramustine and DNA minor groove binder distamycin A.

Baraldi PG, Romagnoli R, Guadix AE, Pineda de las Infantas MJ, Gallo MA, Espinosa A, Martinez A, Bingham JP, Hartley JA. Baraldi PG, et al. Among authors: espinosa a. J Med Chem. 2002 Aug 15;45(17):3630-8. doi: 10.1021/jm011113b. J Med Chem. 2002. PMID: 12166936

3

Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies.

Baraldi PG, Beria I, Cozzi P, Geroni C, Espinosa A, Gallo MA, Entrena A, Bingham JP, Hartley JA, Romagnoli R. Baraldi PG, et al. Among authors: espinosa a. Bioorg Med Chem. 2004 Jul 15;12(14):3911-21. doi: 10.1016/j.bmc.2004.04.045. Bioorg Med Chem. 2004. PMID: 15210158

4

Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity.

Conejo-García A, Pisani L, Núñez Mdel C, Catto M, Nicolotti O, Leonetti F, Campos JM, Gallo MA, Espinosa A, Carotti A. Conejo-García A, et al. Among authors: espinosa a. J Med Chem. 2011 Apr 28;54(8):2627-45. doi: 10.1021/jm101299d. Epub 2011 Apr 6. J Med Chem. 2011. PMID: 21417225

5

Regioselective one-pot synthesis of 9-alkyl-6-chloropyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrazines. Reactivity of aliphatic and aromatic hydrazides.

Unciti-Broceta A, Pineda-de-las-Infantas MJ, Díaz-Mochón JJ, Romagnoli R, Baraldi PG, Gallo MA, Espinosa A. Unciti-Broceta A, et al. Among authors: espinosa a. J Org Chem. 2005 Apr 1;70(7):2878-80. doi: 10.1021/jo0478398. J Org Chem. 2005. PMID: 15787593

6

From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: the shift from differentiating anticancer agents to apoptotic inducers.

Conejo-García A, Núñez Mdel C, Díaz-Gavilán M, Cruz-López O, Gallo MÁ, Espinosa A, Campos JM. Conejo-García A, et al. Among authors: espinosa a. Expert Opin Drug Discov. 2008 Oct;3(10):1223-35. doi: 10.1517/17460441.3.10.1223. Expert Opin Drug Discov. 2008. PMID: 23489079

7

QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be?

Campos J, Núñez MC, Conejo-García A, Sánchez-Martín RM, Hernández-Alcoceba R, Rodríguez-González A, Lacal JC, Gallo MA, Espinosa A. Campos J, et al. Among authors: espinosa a. Curr Med Chem. 2003 Jul;10(13):1095-112. doi: 10.2174/0929867033457539. Curr Med Chem. 2003. PMID: 12678804 Review.

8

Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives.

Braña MF, Gradillas A, Gómez A, Acero N, Llinares F, Muñoz-Mingarro D, Abradelo C, Rey-Stolle F, Yuste M, Campos J, Gallo MA, Espinosa A. Braña MF, et al. Among authors: espinosa a. J Med Chem. 2004 Apr 22;47(9):2236-42. doi: 10.1021/jm0310784. J Med Chem. 2004. PMID: 15084122

9

Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines.

Núñez MC, Díaz-Gavilán M, Conejo-García A, Cruz-López O, Gallo MA, Espinosa A, Campos JM. Núñez MC, et al. Among authors: espinosa a. Curr Med Chem. 2008;15(25):2614-31. doi: 10.2174/092986708785909021. Curr Med Chem. 2008. PMID: 18855682 Review.

10

4,5-dihydro-1H-pyrazole derivatives with inhibitory nNOS activity in rat brain: synthesis and structure-activity relationships.

Camacho ME, León J, Entrena A, Velasco G, Carrión MD, Escames G, Vivó A, Acuña-Castroviejo D, Gallo MA, Espinosa A. Camacho ME, et al. Among authors: espinosa a. J Med Chem. 2004 Nov 4;47(23):5641-50. doi: 10.1021/jm0407714. J Med Chem. 2004. PMID: 15509163

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