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Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents.
Suh YG, Lee YS, Min KH, Park OH, Kim JK, Seung HS, Seo SY, Lee BY, Nam YH, Lee KO, Kim HD, Park HG, Lee J, Oh U, Lim JO, Kang SU, Kil MJ, Koo JY, Shin SS, Joo YH, Kim JK, Jeong YS, Kim SY, Park YH. Suh YG, et al. Among authors: kim jk, kim sy, kim hd. J Med Chem. 2005 Sep 8;48(18):5823-36. doi: 10.1021/jm0502790. J Med Chem. 2005. PMID: 16134949
Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase Inhibitor.
Yu Y, Jang M, Miyashiro J, Clark RF, Zhu GD, Gong J, Dai Y, Frey RR, Penning TD, Kim H, Lee HK, Kim JK, Ryu KM, Park SJ, Yoon T, Li T, Kurnick MD, Kapecki NJ, Li L, Gorman JV, Montgomery DA, Manaves V, Bromberg KD, Doktor SZ, Thakur A, Wang J, Smith HA, Buchanan FG, Ferguson DC, Torrent M, Jakob CG, Qiu W, Upadhyay AK, Martin RL, Lai A, Michaelides MR. Yu Y, et al. Among authors: kim h, kim jk. J Med Chem. 2024 Oct 10;67(19):17000-17032. doi: 10.1021/acs.jmedchem.4c01450. Epub 2024 Sep 16. J Med Chem. 2024. PMID: 39283694
PAR-5359, a well-balanced PPARalpha/gamma dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo.
Kim MK, Chae YN, Son MH, Kim SH, Kim JK, Moon HS, Park CS, Bae MH, Kim E, Han T, Choi HH, Shin YA, Ahn BN, Lee CH, Lim JI, Shin CY. Kim MK, et al. Among authors: kim e, kim jk, kim sh. Eur J Pharmacol. 2008 Oct 24;595(1-3):119-25. doi: 10.1016/j.ejphar.2008.07.066. Epub 2008 Aug 12. Eur J Pharmacol. 2008. PMID: 18727927
PAR-1622 is a selective peroxisome proliferator-activated receptor gamma partial activator with preserved antidiabetic efficacy and broader safety profile for fluid retention.
Kim MK, Chae YN, Kim HS, Choi SH, Son MH, Kim SH, Kim JK, Moon HS, Park SK, Shin YA, Kim JG, Lee CH, Lim JI, Shin CY. Kim MK, et al. Among authors: kim jk, kim sh, kim hs, kim jg. Arch Pharm Res. 2009 May;32(5):721-7. doi: 10.1007/s12272-009-1511-8. Epub 2009 May 27. Arch Pharm Res. 2009. PMID: 19471887
5,501 results