Huibregtse JM - Search Results

1

The -4 phenylalanine is required for substrate ubiquitination catalyzed by HECT ubiquitin ligases.

Salvat C, Wang G, Dastur A, Lyon N, Huibregtse JM. Salvat C, et al. Among authors: huibregtse jm. J Biol Chem. 2004 Apr 30;279(18):18935-43. doi: 10.1074/jbc.M312201200. Epub 2004 Feb 13. J Biol Chem. 2004. PMID: 14966115 Free article.

2

Expression and assay of HECT domain ligases.

Beaudenon S, Dastur A, Huibregtse JM. Beaudenon S, et al. Among authors: huibregtse jm. Methods Enzymol. 2005;398:112-25. doi: 10.1016/S0076-6879(05)98011-7. Methods Enzymol. 2005. PMID: 16275324

3

Herc5, an interferon-induced HECT E3 enzyme, is required for conjugation of ISG15 in human cells.

Dastur A, Beaudenon S, Kelley M, Krug RM, Huibregtse JM. Dastur A, et al. Among authors: huibregtse jm. J Biol Chem. 2006 Feb 17;281(7):4334-8. doi: 10.1074/jbc.M512830200. Epub 2005 Dec 28. J Biol Chem. 2006. PMID: 16407192 Free article.

4

The deubiquitinating enzyme Ubp2 modulates Rsp5-dependent Lys63-linked polyubiquitin conjugates in Saccharomyces cerevisiae.

Kee Y, Muñoz W, Lyon N, Huibregtse JM. Kee Y, et al. Among authors: huibregtse jm. J Biol Chem. 2006 Dec 1;281(48):36724-31. doi: 10.1074/jbc.M608756200. Epub 2006 Oct 6. J Biol Chem. 2006. PMID: 17028178 Free article.

5

A single PXY motif located within the carboxyl terminus of Spt23p and Mga2p mediates a physical and functional interaction with ubiquitin ligase Rsp5p.

Shcherbik N, Kee Y, Lyon N, Huibregtse JM, Haines DS. Shcherbik N, et al. Among authors: huibregtse jm. J Biol Chem. 2004 Dec 17;279(51):53892-8. doi: 10.1074/jbc.M410325200. Epub 2004 Oct 5. J Biol Chem. 2004. PMID: 15466864 Free article.

6

Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.

O'Connor HF, Lyon N, Leung JW, Agarwal P, Swaim CD, Miller KM, Huibregtse JM. O'Connor HF, et al. Among authors: huibregtse jm. EMBO Rep. 2015 Dec;16(12):1699-712. doi: 10.15252/embr.201540620. Epub 2015 Oct 27. EMBO Rep. 2015. PMID: 26508657 Free PMC article.

7

The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme.

Kee Y, Lyon N, Huibregtse JM. Kee Y, et al. Among authors: huibregtse jm. EMBO J. 2005 Jul 6;24(13):2414-24. doi: 10.1038/sj.emboj.7600710. Epub 2005 Jun 2. EMBO J. 2005. PMID: 15933713 Free PMC article.

8

Functional domains of the Rsp5 ubiquitin-protein ligase.

Wang G, Yang J, Huibregtse JM. Wang G, et al. Among authors: huibregtse jm. Mol Cell Biol. 1999 Jan;19(1):342-52. doi: 10.1128/MCB.19.1.342. Mol Cell Biol. 1999. PMID: 9858558 Free PMC article.

9

Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway.

Wang G, McCaffery JM, Wendland B, Dupré S, Haguenauer-Tsapis R, Huibregtse JM. Wang G, et al. Among authors: huibregtse jm. Mol Cell Biol. 2001 May;21(10):3564-75. doi: 10.1128/MCB.21.10.3564-3575.2001. Mol Cell Biol. 2001. PMID: 11313482 Free PMC article.

10

The ISG15 conjugation system broadly targets newly synthesized proteins: implications for the antiviral function of ISG15.

Durfee LA, Lyon N, Seo K, Huibregtse JM. Durfee LA, et al. Among authors: huibregtse jm. Mol Cell. 2010 Jun 11;38(5):722-32. doi: 10.1016/j.molcel.2010.05.002. Mol Cell. 2010. PMID: 20542004 Free PMC article.

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