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Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development.
Ye L, MacDougall M, Zhang S, Xie Y, Zhang J, Li Z, Lu Y, Mishina Y, Feng JQ. Ye L, et al. Among authors: zhang s, zhang j. J Biol Chem. 2004 Apr 30;279(18):19141-8. doi: 10.1074/jbc.M400490200. Epub 2004 Feb 13. J Biol Chem. 2004. PMID: 14966118 Free article.
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling.
Li X, Zhang Y, Kang H, Liu W, Liu P, Zhang J, Harris SE, Wu D. Li X, et al. Among authors: zhang j, zhang y. J Biol Chem. 2005 May 20;280(20):19883-7. doi: 10.1074/jbc.M413274200. Epub 2005 Mar 18. J Biol Chem. 2005. PMID: 15778503 Free article.
GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome.
Pi M, Chen L, Huang MZ, Zhu W, Ringhofer B, Luo J, Christenson L, Li B, Zhang J, Jackson PD, Faber P, Brunden KR, Harrington JJ, Quarles LD. Pi M, et al. Among authors: zhang j. PLoS One. 2008;3(12):e3858. doi: 10.1371/journal.pone.0003858. Epub 2008 Dec 3. PLoS One. 2008. PMID: 19050760 Free PMC article.
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