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The osteopetrotic mutation toothless (tl) is a loss-of-function frameshift mutation in the rat Csf1 gene: Evidence of a crucial role for CSF-1 in osteoclastogenesis and endochondral ossification.
Van Wesenbeeck L, Odgren PR, MacKay CA, D'Angelo M, Safadi FF, Popoff SN, Van Hul W, Marks SC Jr. Van Wesenbeeck L, et al. Among authors: odgren pr. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14303-8. doi: 10.1073/pnas.202332999. Epub 2002 Oct 11. Proc Natl Acad Sci U S A. 2002. PMID: 12379742 Free PMC article.
Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans.
Van Wesenbeeck L, Odgren PR, Coxon FP, Frattini A, Moens P, Perdu B, MacKay CA, Van Hul E, Timmermans JP, Vanhoenacker F, Jacobs R, Peruzzi B, Teti A, Helfrich MH, Rogers MJ, Villa A, Van Hul W. Van Wesenbeeck L, et al. Among authors: odgren pr. J Clin Invest. 2007 Apr;117(4):919-30. doi: 10.1172/JCI30328. J Clin Invest. 2007. PMID: 17404618 Free PMC article.
Chemokine and chemokine receptor expression during colony stimulating factor-1-induced osteoclast differentiation in the toothless osteopetrotic rat: a key role for CCL9 (MIP-1gamma) in osteoclastogenesis in vivo and in vitro.
Yang M, Mailhot G, MacKay CA, Mason-Savas A, Aubin J, Odgren PR. Yang M, et al. Among authors: odgren pr. Blood. 2006 Mar 15;107(6):2262-70. doi: 10.1182/blood-2005-08-3365. Epub 2005 Nov 22. Blood. 2006. PMID: 16304045 Free PMC article.
Septoclast deficiency accompanies postnatal growth plate chondrodysplasia in the toothless (tl) osteopetrotic, colony-stimulating factor-1 (CSF-1)-deficient rat and is partially responsive to CSF-1 injections.
Gartland A, Mason-Savas A, Yang M, MacKay CA, Birnbaum MJ, Odgren PR. Gartland A, et al. Among authors: odgren pr. Am J Pathol. 2009 Dec;175(6):2668-75. doi: 10.2353/ajpath.2009.090185. Epub 2009 Nov 5. Am J Pathol. 2009. PMID: 19893052 Free PMC article.
61 results