Fearns C - Search Results

1

Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.

Lo JF, Hayashi M, Woo-Kim S, Tian B, Huang JF, Fearns C, Takayama S, Zapata JM, Yang Y, Lee JD. Lo JF, et al. Among authors: fearns c. Mol Cell Biol. 2004 Mar;24(6):2226-36. doi: 10.1128/MCB.24.6.2226-2236.2004. Mol Cell Biol. 2004. PMID: 14993262 Free PMC article.

2

Tid1, the human homologue of a Drosophila tumor suppressor, reduces the malignant activity of ErbB-2 in carcinoma cells.

Kim SW, Chao TH, Xiang R, Lo JF, Campbell MJ, Fearns C, Lee JD. Kim SW, et al. Among authors: fearns c. Cancer Res. 2004 Nov 1;64(21):7732-9. doi: 10.1158/0008-5472.CAN-04-1323. Cancer Res. 2004. PMID: 15520177

3

Tid1 is required for T cell transition from double-negative 3 to double-positive stages.

Lo JF, Zhou H, Fearns C, Reisfeld RA, Yang Y, Lee JD. Lo JF, et al. Among authors: fearns c. J Immunol. 2005 May 15;174(10):6105-12. doi: 10.4049/jimmunol.174.10.6105. J Immunol. 2005. PMID: 15879105

4

Big mitogen-activated protein kinase 1/extracellular signal-regulated kinase 5 signaling pathway is essential for tumor-associated angiogenesis.

Hayashi M, Fearns C, Eliceiri B, Yang Y, Lee JD. Hayashi M, et al. Among authors: fearns c. Cancer Res. 2005 Sep 1;65(17):7699-706. doi: 10.1158/0008-5472.CAN-04-4540. Cancer Res. 2005. PMID: 16140937

5

Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interleukin-8.

Kim SW, Hayashi M, Lo JF, Fearns C, Xiang R, Lazennec G, Yang Y, Lee JD. Kim SW, et al. Among authors: fearns c. Cancer Res. 2005 Oct 1;65(19):8784-91. doi: 10.1158/0008-5472.CAN-04-4422. Cancer Res. 2005. PMID: 16204048

6

A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy.

Hayashi M, Imanaka-Yoshida K, Yoshida T, Wood M, Fearns C, Tatake RJ, Lee JD. Hayashi M, et al. Among authors: fearns c. Nat Med. 2006 Jan;12(1):128-32. doi: 10.1038/nm1327. Epub 2005 Dec 4. Nat Med. 2006. PMID: 16327803

7

Nuclear factor kappaB (NF-kappaB) activation primes cells to a pro-inflammatory polarized response to a Toll-like receptor 7 (TLR7) agonist.

Lee J, Hayashi M, Lo JF, Fearns C, Chu WM, Luo Y, Xiang R, Chuang TH. Lee J, et al. Among authors: fearns c. Biochem J. 2009 Jun 26;421(2):301-10. doi: 10.1042/BJ20090013. Biochem J. 2009. PMID: 19426145 Free PMC article.

8

Combined integrin phosphoproteomic analyses and small interfering RNA--based functional screening identify key regulators for cancer cell adhesion and migration.

Chen Y, Lu B, Yang Q, Fearns C, Yates JR 3rd, Lee JD. Chen Y, et al. Among authors: fearns c. Cancer Res. 2009 Apr 15;69(8):3713-20. doi: 10.1158/0008-5472.CAN-08-2515. Epub 2009 Apr 7. Cancer Res. 2009. PMID: 19351860 Free PMC article.

9

Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein.

Yang Q, Deng X, Lu B, Cameron M, Fearns C, Patricelli MP, Yates JR 3rd, Gray NS, Lee JD. Yang Q, et al. Among authors: fearns c. Cancer Cell. 2010 Sep 14;18(3):258-67. doi: 10.1016/j.ccr.2010.08.008. Cancer Cell. 2010. PMID: 20832753 Free PMC article.

10

Kinome siRNA screen identifies SMG-1 as a negative regulator of hypoxia-inducible factor-1alpha in hypoxia.

Chen RQ, Yang QK, Chen YL, Oliveira VA, Dalton WS, Fearns C, Lee JD. Chen RQ, et al. Among authors: fearns c. J Biol Chem. 2009 Jun 19;284(25):16752-16758. doi: 10.1074/jbc.M109.014316. Epub 2009 Apr 30. J Biol Chem. 2009. PMID: 19406746 Free PMC article.

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