Lavreysen H - Search Results

1

Metabotropic glutamate 1 receptor distribution and occupancy in the rat brain: a quantitative autoradiographic study using [3H]R214127.

Lavreysen H, Pereira SN, Leysen JE, Langlois X, Lesage AS. Lavreysen H, et al. Neuropharmacology. 2004 Apr;46(5):609-19. doi: 10.1016/j.neuropharm.2003.11.014. Neuropharmacology. 2004. PMID: 14996538

2

Supersensitivity of human metabotropic glutamate 1a receptor signaling in L929sA cells.

Lavreysen H, Le Poul E, Van Gompel P, Dillen L, Leysen JE, Lesage AS. Lavreysen H, et al. Mol Pharmacol. 2002 May;61(5):1244-54. doi: 10.1124/mol.61.5.1244. Mol Pharmacol. 2002. PMID: 11961143

3

[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists.

Lavreysen H, Janssen C, Bischoff F, Langlois X, Leysen JE, Lesage AS. Lavreysen H, et al. Mol Pharmacol. 2003 May;63(5):1082-93. doi: 10.1124/mol.63.5.1082. Mol Pharmacol. 2003. PMID: 12695537

4

JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist.

Lavreysen H, Wouters R, Bischoff F, Nóbrega Pereira S, Langlois X, Blokland S, Somers M, Dillen L, Lesage AS. Lavreysen H, et al. Neuropharmacology. 2004 Dec;47(7):961-72. doi: 10.1016/j.neuropharm.2004.08.007. Neuropharmacology. 2004. PMID: 15555631

5

Antagonist-induced supersensitivity of mGlu1 receptor signalling in cerebellar granule cells.

Lavreysen H, Willemoens T, Leysen JE, Lesage AS. Lavreysen H, et al. Eur J Neurosci. 2005 Mar;21(6):1610-6. doi: 10.1111/j.1460-9568.2005.03998.x. Eur J Neurosci. 2005. PMID: 15845088

6

Effects of mGlu1 receptor blockade on anxiety-related behaviour in the rat lick suppression test.

Steckler T, Lavreysen H, Oliveira AM, Aerts N, Van Craenendonck H, Prickaerts J, Megens A, Lesage AS. Steckler T, et al. Among authors: lavreysen h. Psychopharmacology (Berl). 2005 Apr;179(1):198-206. doi: 10.1007/s00213-004-2056-7. Epub 2004 Dec 4. Psychopharmacology (Berl). 2005. PMID: 15821950

7

Metabotropic glutamate receptors: their therapeutic potential in anxiety.

Spooren W, Lesage A, Lavreysen H, Gasparini F, Steckler T. Spooren W, et al. Among authors: lavreysen h. Curr Top Behav Neurosci. 2010;2:391-413. doi: 10.1007/7854_2010_36. Curr Top Behav Neurosci. 2010. PMID: 21309118 Review.

8

Synthesis, evaluation, and radiolabeling of new potent positive allosteric modulators of the metabotropic glutamate receptor 2 as potential tracers for positron emission tomography imaging.

Andrés JI, Alcázar J, Cid JM, De Angelis M, Iturrino L, Langlois X, Lavreysen H, Trabanco AA, Celen S, Bormans G. Andrés JI, et al. Among authors: lavreysen h. J Med Chem. 2012 Oct 25;55(20):8685-99. doi: 10.1021/jm300912k. Epub 2012 Oct 11. J Med Chem. 2012. PMID: 22992024

9

Pharmacological characterization of JNJ-40068782, a new potent, selective, and systemically active positive allosteric modulator of the mGlu2 receptor and its radioligand [3H]JNJ-40068782.

Lavreysen H, Langlois X, Ahnaou A, Drinkenburg W, te Riele P, Biesmans I, Van der Linden I, Peeters L, Megens A, Wintmolders C, Cid JM, Trabanco AA, Andrés JI, Dautzenberg FM, Lütjens R, Macdonald G, Atack JR. Lavreysen H, et al. J Pharmacol Exp Ther. 2013 Sep;346(3):514-27. doi: 10.1124/jpet.113.204990. Epub 2013 Jun 13. J Pharmacol Exp Ther. 2013. PMID: 23766542

10

Characterization of 2-[[4-fluoro-3-(trifluoromethyl)phenyl]amino]-4-(4-pyridinyl)-5-thiazolemethanol (JNJ-1930942), a novel positive allosteric modulator of the {alpha}7 nicotinic acetylcholine receptor.

Dinklo T, Shaban H, Thuring JW, Lavreysen H, Stevens KE, Zheng L, Mackie C, Grantham C, Vandenberk I, Meulders G, Peeters L, Verachtert H, De Prins E, Lesage AS. Dinklo T, et al. Among authors: lavreysen h. J Pharmacol Exp Ther. 2011 Feb;336(2):560-74. doi: 10.1124/jpet.110.173245. Epub 2010 Nov 17. J Pharmacol Exp Ther. 2011. PMID: 21084390

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