Angehrn P - Search Results

1

New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine.

Angehrn P, Buchmann S, Funk C, Goetschi E, Gmuender H, Hebeisen P, Kostrewa D, Link H, Luebbers T, Masciadri R, Nielsen J, Reindl P, Ricklin F, Schmitt-Hoffmann A, Theil FP. Angehrn P, et al. J Med Chem. 2004 Mar 11;47(6):1487-513. doi: 10.1021/jm0310232. J Med Chem. 2004. PMID: 14998336

2

A new DNA gyrase inhibitor subclass of the cyclothialidine family based on a bicyclic dilactam-lactone scaffold. Synthesis and antibacterial properties.

Angehrn P, Goetschi E, Gmuender H, Hebeisen P, Hennig M, Kuhn B, Luebbers T, Reindl P, Ricklin F, Schmitt-Hoffmann A. Angehrn P, et al. J Med Chem. 2011 Apr 14;54(7):2207-24. doi: 10.1021/jm1014023. Epub 2011 Mar 9. J Med Chem. 2011. PMID: 21388139

3

Cyclothialidine and its congeners: a new class of DNA gyrase inhibitors.

Goetschi E, Angehrn P, Gmuender H, Hebeisen P, Link H, Masciadri R, Nielsen J. Goetschi E, et al. Among authors: angehrn p. Pharmacol Ther. 1993 Nov;60(2):367-80. doi: 10.1016/0163-7258(93)90017-8. Pharmacol Ther. 1993. PMID: 8022866 Review.

4

Novel ketolide antibiotics with a fused five-membered lactone ring--synthesis, physicochemical and antimicrobial properties.

Hunziker D, Wyss PC, Angehrn P, Mueller A, Marty HP, Halm R, Kellenberger L, Bitsch V, Biringer G, Arnold W, Stämpfli A, Schmitt-Hoffmann A, Cousot D. Hunziker D, et al. Among authors: angehrn p. Bioorg Med Chem. 2004 Jul 1;12(13):3503-19. doi: 10.1016/j.bmc.2004.04.039. Bioorg Med Chem. 2004. PMID: 15186835

5

Synthesis and structure-activity relationship of (lactamylvinyl)cephalosporins exhibiting activity against staphylococci, pneumococci, and enterococci.

Heinze-Krauss I, Angehrn P, Guerry P, Hebeisen P, Hubschwerlen C, Kompis I, Page MG, Richter HG, Runtz V, Stalder H, Weiss U, Wei CC. Heinze-Krauss I, et al. Among authors: angehrn p. J Med Chem. 1996 Apr 26;39(9):1864-71. doi: 10.1021/jm950886v. J Med Chem. 1996. PMID: 8627610

6

Pyrimido[1,6-a]benzimidazoles: a new class of DNA gyrase inhibitors.

Hubschwerlen C, Pflieger P, Specklin JL, Gubernator K, Gmünder H, Angehrn P, Kompis I. Hubschwerlen C, et al. Among authors: angehrn p. J Med Chem. 1992 Apr 17;35(8):1385-92. doi: 10.1021/jm00086a006. J Med Chem. 1992. PMID: 1315393

7

Design, synthesis, and structure-activity relationship studies of new phenolic DNA gyrase inhibitors.

Lübbers T, Angehrn P, Gmünder H, Herzig S. Lübbers T, et al. Among authors: angehrn p. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4708-14. doi: 10.1016/j.bmcl.2006.12.065. Epub 2006 Dec 22. Bioorg Med Chem Lett. 2007. PMID: 17632001

8

Design, synthesis, and structure-activity relationship studies of ATP analogues as DNA gyrase inhibitors.

Lübbers T, Angehrn P, Gmünder H, Herzig S, Kulhanek J. Lübbers T, et al. Among authors: angehrn p. Bioorg Med Chem Lett. 2000 Apr 17;10(8):821-6. doi: 10.1016/s0960-894x(00)00109-8. Bioorg Med Chem Lett. 2000. PMID: 10782694

9

In vitro and in vivo properties of Ro 63-9141, a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococci.

Hebeisen P, Heinze-Krauss I, Angehrn P, Hohl P, Page MG, Then RL. Hebeisen P, et al. Among authors: angehrn p. Antimicrob Agents Chemother. 2001 Mar;45(3):825-36. doi: 10.1128/AAC.45.3.825-836.2001. Antimicrob Agents Chemother. 2001. PMID: 11181368 Free PMC article.

10

New anti-MRSA and anti-VRE carbapenems; synthesis and structure-activity relationships of 1beta-methyl-2-(thiazol-2-ylthio)carbapenems.

Sunagawa M, Itoh M, Kubota K, Sasaki A, Ueda Y, Angehrn P, Bourson A, Goetschi E, Hebeisen P, Then RL. Sunagawa M, et al. Among authors: angehrn p. J Antibiot (Tokyo). 2002 Aug;55(8):722-57. doi: 10.7164/antibiotics.55.722. J Antibiot (Tokyo). 2002. PMID: 12374386 Free article.

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