Chen J - Search Results

1

Activation of mTOR signaling by novel fluoromethylene phosphonate analogues of phosphatidic acid.

Xu Y, Fang Y, Chen J, Prestwich GD. Xu Y, et al. Among authors: chen j. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1461-4. doi: 10.1016/j.bmcl.2004.01.020. Bioorg Med Chem Lett. 2004. PMID: 15006382

2

A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.

Chen J, Fang Y. Chen J, et al. Biochem Pharmacol. 2002 Oct 1;64(7):1071-7. doi: 10.1016/s0006-2952(02)01263-7. Biochem Pharmacol. 2002. PMID: 12234610 Review.

3

PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1.

Fang Y, Park IH, Wu AL, Du G, Huang P, Frohman MA, Walker SJ, Brown HA, Chen J. Fang Y, et al. Among authors: chen j. Curr Biol. 2003 Dec 2;13(23):2037-44. doi: 10.1016/j.cub.2003.11.021. Curr Biol. 2003. PMID: 14653992 Free article.

4

XPLN is an endogenous inhibitor of mTORC2.

Khanna N, Fang Y, Yoon MS, Chen J. Khanna N, et al. Among authors: chen j. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):15979-84. doi: 10.1073/pnas.1310434110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043828 Free PMC article.

5

Duration of rapamycin treatment has differential effects on metabolism in mice.

Fang Y, Westbrook R, Hill C, Boparai RK, Arum O, Spong A, Wang F, Javors MA, Chen J, Sun LY, Bartke A. Fang Y, et al. Among authors: chen j. Cell Metab. 2013 Mar 5;17(3):456-62. doi: 10.1016/j.cmet.2013.02.008. Cell Metab. 2013. PMID: 23473038 Free PMC article.

6

Effects of rapamycin on growth hormone receptor knockout mice.

Fang Y, Hill CM, Darcy J, Reyes-Ordoñez A, Arauz E, McFadden S, Zhang C, Osland J, Gao J, Zhang T, Frank SJ, Javors MA, Yuan R, Kopchick JJ, Sun LY, Chen J, Bartke A. Fang Y, et al. Among authors: chen j. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1495-E1503. doi: 10.1073/pnas.1717065115. Epub 2018 Jan 29. Proc Natl Acad Sci U S A. 2018. PMID: 29378959 Free PMC article.

7

Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.

Simons M, Gault WJ, Gotthardt D, Rohatgi R, Klein TJ, Shao Y, Lee HJ, Wu AL, Fang Y, Satlin LM, Dow JT, Chen J, Zheng J, Boutros M, Mlodzik M. Simons M, et al. Among authors: chen j. Nat Cell Biol. 2009 Mar;11(3):286-94. doi: 10.1038/ncb1836. Epub 2009 Feb 22. Nat Cell Biol. 2009. PMID: 19234454 Free PMC article.

8

Mammalian target of rapamycin (mTOR) signaling is required for a late-stage fusion process during skeletal myotube maturation.

Park IH, Chen J. Park IH, et al. Among authors: chen j. J Biol Chem. 2005 Sep 9;280(36):32009-17. doi: 10.1074/jbc.M506120200. Epub 2005 Jul 25. J Biol Chem. 2005. PMID: 16043480 Free article.

9

mTOR signaling: PLD takes center stage.

Sun Y, Chen J. Sun Y, et al. Among authors: chen j. Cell Cycle. 2008 Oct;7(20):3118-23. doi: 10.4161/cc.7.20.6881. Epub 2008 Oct 27. Cell Cycle. 2008. PMID: 18927511 Review.

10

Phosphatidic acid activates mammalian target of rapamycin complex 1 (mTORC1) kinase by displacing FK506 binding protein 38 (FKBP38) and exerting an allosteric effect.

Yoon MS, Sun Y, Arauz E, Jiang Y, Chen J. Yoon MS, et al. Among authors: chen j. J Biol Chem. 2011 Aug 26;286(34):29568-74. doi: 10.1074/jbc.M111.262816. Epub 2011 Jul 7. J Biol Chem. 2011. PMID: 21737445 Free PMC article.

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