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Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s.
Jenkins CM, Han X, Mancuso DJ, Gross RW. Jenkins CM, et al. Among authors: mancuso dj. J Biol Chem. 2002 Sep 6;277(36):32807-14. doi: 10.1074/jbc.M202568200. Epub 2002 Jun 27. J Biol Chem. 2002. PMID: 12089145 Free article.
The highly selective production of 2-arachidonoyl lysophosphatidylcholine catalyzed by purified calcium-independent phospholipase A2gamma: identification of a novel enzymatic mediator for the generation of a key branch point intermediate in eicosanoid signaling.
Yan W, Jenkins CM, Han X, Mancuso DJ, Sims HF, Yang K, Gross RW. Yan W, et al. Among authors: mancuso dj. J Biol Chem. 2005 Jul 22;280(29):26669-79. doi: 10.1074/jbc.M502358200. Epub 2005 May 20. J Biol Chem. 2005. PMID: 15908428 Free article.
Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.
Mancuso DJ, Han X, Jenkins CM, Lehman JJ, Sambandam N, Sims HF, Yang J, Yan W, Yang K, Green K, Abendschein DR, Saffitz JE, Gross RW. Mancuso DJ, et al. J Biol Chem. 2007 Mar 23;282(12):9216-27. doi: 10.1074/jbc.M607307200. Epub 2007 Jan 9. J Biol Chem. 2007. PMID: 17213206 Free article.
Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype.
Mancuso DJ, Sims HF, Han X, Jenkins CM, Guan SP, Yang K, Moon SH, Pietka T, Abumrad NA, Schlesinger PH, Gross RW. Mancuso DJ, et al. J Biol Chem. 2007 Nov 30;282(48):34611-22. doi: 10.1074/jbc.M707795200. Epub 2007 Oct 8. J Biol Chem. 2007. PMID: 17923475 Free PMC article.
45 results