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Page 1
Geometrically constrained analogues of N-benzylindolylglyoxylylamides: [1, 2, 4]triazino[4, 3-a]benzimidazol-4(10H)-one derivatives as potential new ligands at the benzodiazepine receptor.
Primofiore G, Da Settimo F, Taliani S, Marini AM, Simorini F, Novellino E, Greco G, Trincavelli L, Martini C. Primofiore G, et al. Among authors: simorini f. Arch Pharm (Weinheim). 2003 Sep;336(9):413-21. doi: 10.1002/ardp.200300788. Arch Pharm (Weinheim). 2003. PMID: 14528489
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells.
Chelli B, Rossi L, Da Pozzo E, Costa B, Spinetti F, Rechichi M, Salvetti A, Lena A, Simorini F, Vanacore R, Scatena F, Da Settimo F, Gremigni V, Martini C. Chelli B, et al. Among authors: simorini f. Chembiochem. 2005 Jun;6(6):1082-8. doi: 10.1002/cbic.200400350. Chembiochem. 2005. PMID: 15883977
Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.
Da Settimo F, Primofiore G, La Motta C, Taliani S, Simorini F, Marini AM, Mugnaini L, Lavecchia A, Novellino E, Tuscano D, Martini C. Da Settimo F, et al. Among authors: simorini f. J Med Chem. 2005 Aug 11;48(16):5162-74. doi: 10.1021/jm050136d. J Med Chem. 2005. PMID: 16078836
New fluorescent 2-phenylindolglyoxylamide derivatives as probes targeting the peripheral-type benzodiazepine receptor: design, synthesis, and biological evaluation.
Taliani S, Simorini F, Sergianni V, La Motta C, Da Settimo F, Cosimelli B, Abignente E, Greco G, Novellino E, Rossi L, Gremigni V, Spinetti F, Chelli B, Martini C. Taliani S, et al. Among authors: simorini f. J Med Chem. 2007 Jan 25;50(2):404-7. doi: 10.1021/jm061137o. J Med Chem. 2007. PMID: 17228885
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.
Primofiore G, Taliani S, Da Settimo F, Marini AM, La Motta C, Simorini F, Patrizi MP, Sergianni V, Novellino E, Greco G, Cosimelli B, Calderone V, Montali M, Besnard F, Martini C. Primofiore G, et al. Among authors: simorini f. J Med Chem. 2007 Apr 5;50(7):1627-34. doi: 10.1021/jm0607707. Epub 2007 Mar 3. J Med Chem. 2007. PMID: 17335185
46 results